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The nucleotide sequence of a cloned rabbit chromosomal DNA segment of 1620 nucleotides length which contains a beta-globin gene is presented. The coding regions are separated into three blocks by two intervening sequences of 126 and 573 base pairs, respectively. The rabbit sequence was compared with a homologous mouse sequence. The segments flanking the rabbit gene, as well as the coding regions, the 5' noncoding and part of the 3' noncoding messenger RNA sequences are similar to those of the mouse gene; the homologous introns, despite identical location, are distinctly dissimilar except for the junction regions. Homologous introns may be derived from common ancestral introns by large insertions and deletions rather than be multiple point mutations.
A van Ooyen, and
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N Mantei, and
C Weissmann
July 1987,
Nucleic acids research,
A van Ooyen, and
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C Weissmann
October 1977,
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A van Ooyen, and
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N Mantei, and
C Weissmann
September 1979,
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A van Ooyen, and
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August 1987,
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A van Ooyen, and
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May 1994,
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A van Ooyen, and
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C Weissmann
March 1990,
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A van Ooyen, and
J van den Berg, and
N Mantei, and
C Weissmann
October 1984,
Nucleic acids research,
A van Ooyen, and
J van den Berg, and
N Mantei, and
C Weissmann
November 1984,
Cell,
A van Ooyen, and
J van den Berg, and
N Mantei, and
C Weissmann
December 1978,
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A van Ooyen, and
J van den Berg, and
N Mantei, and
C Weissmann
April 1981,
Nucleic acids research,
