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Mass phenotyping of isoniazid inactivators by automated determination of acetylisoniazid in urine.
1974
P Varughese, and E J Hamilton, and L Eidus
Associated MeSH Terms
Cite
UI
MeSH Term
Description
Entries
D007538
Isoniazid
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Isonicotinic Acid Hydrazide,Ftivazide,Isonex,Isonicotinic Acid Vanillylidenehydrazide,Phthivazid,Phthivazide,Tubazide,Acid Vanillylidenehydrazide, Isonicotinic,Hydrazide, Isonicotinic Acid,Vanillylidenehydrazide, Isonicotinic Acid
D008722
Methods
A series of steps taken in order to conduct research.
Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D010641
Phenotype
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
Phenotypes
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006834
Hydrazines
Substituted derivatives of hydrazine (formula H2N-NH2).
Hydrazide
D001322
Autoanalysis
Method of analyzing chemicals using automation.
Autoanalyses
Related Publications
P Varughese, and E J Hamilton, and L Eidus
[Determination of isoniazid and acetylisoniazid in the urine for phenotyping isoniazid inactivators].
April 1983, Zhonghua jie he he hu xi xi ji bing za zhi = Chinese journal of tuberculosis and respiratory diseases,
P Varughese, and E J Hamilton, and L Eidus
Urine test for phenotyping isoniazid inactivators.
October 1971, The American review of respiratory disease,
P Varughese, and E J Hamilton, and L Eidus
Ion-pair high-performance liquid chromatographic determination of isoniazid and acetylisoniazid in plasma and urine. Application for acetylator phenotyping.
May 1985, Journal of chromatography,
P Varughese, and E J Hamilton, and L Eidus
Classification of subjects as slow or rapid inactivators of isoniazid oral administration of a slow-release preparation of isoniazid and determination of the ratio of acetylisoniazid to isoniazid in urine.
February 1975, The Indian journal of medical research,
P Varughese, and E J Hamilton, and L Eidus
Simplified screening test for phenotyping of isoniazid inactivators.
February 1973, International journal of clinical pharmacology, therapy and toxicology,
P Varughese, and E J Hamilton, and L Eidus
Classification of subjects as slow or rapid inactivators of isoniazid based on the ratio of acetylisoniazid to isoniazid in urine determined by a simple colorimetric method.
October 1976, The Indian journal of medical research,
P Varughese, and E J Hamilton, and L Eidus
Isoniazid/acetylisoniazid urine concentrations: markers of adherence to isoniazid preventive therapy in children.
May 2014, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease,
P Varughese, and E J Hamilton, and L Eidus
Determination of acetylator phenotype based on the ratio of acetylisoniazid to isoniazid in urine following an oral dose of ordinary isoniazid.
January 1976, The Indian journal of medical research,
P Varughese, and E J Hamilton, and L Eidus
Isoniazid inactivators.
May 1978, The Journal of the Association of Physicians of India,
P Varughese, and E J Hamilton, and L Eidus
Sodium nitroprusside test for the detection of isoniazid and acetylisoniazid in urine.
March 1967, Tubercle,
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