[Cervical ripening in late pregnancy and at term]. 1979

G Lamberti

Cervical ripening before labors is not an exclusively passive process by uterine contractions. On the contrary, we can find a lot of highly active processes in the cervical connective tissue with changes in metabolism of the cells leading to changes in the ground substance and the organisation and structure of collagenous fibres. We do not as yet know the trigger mechanisms of the prepartum cervical rpiening. Probably prostaglandins and relaxin are such triggering substances. At present, our new understanding of this active cervical process does not help the obstetrician. There is no laboratory test up to now. Cervical ripeness can only be examined on the basis of clinical criteria: length, consistency, position, and dilatation of the cervix uteri and station of the fetal head. The most usual score of cervical ripeness is Bishop's Pelvic-score. A high scoring excludes failures of induction of labor. But the rate of wrong prognosis, concerning efficiency of induction and time of labor is relatively high in cases with low rating of cervical ripeness. A more differentiated scoring of some of the criteria and some weighing of these seems to lead to better prognosis. On the other hand, recent clinical experiences with prostaglandins lead us to expect that we will be able to induce cervical ripeness.

UI MeSH Term Description Entries
D007743 Labor, Obstetric The repetitive uterine contraction during childbirth which is associated with the progressive dilation of the uterine cervix (CERVIX UTERI). Successful labor results in the expulsion of the FETUS and PLACENTA. Obstetric labor can be spontaneous or induced (LABOR, INDUCED). Obstetric Labor
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011453 Prostaglandins A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes. Prostaglandin,Prostanoid,Prostanoids
D011509 Proteoglycans Glycoproteins which have a very high polysaccharide content. Proteoglycan,Proteoglycan Type H
D002584 Cervix Uteri The neck portion of the UTERUS between the lower isthmus and the VAGINA forming the cervical canal. Cervical Canal of the Uterus,Cervical Canal, Uterine,Ectocervix,Endocervical Canal,Endocervix,External Os Cervix,External Os of the Cervix,Uterine Cervical Canal,Cervix,Cervixes,Uterine Cervix,Canal, Endocervical,Canal, Uterine Cervical,Cervix, External Os,Cervix, Uterine,Endocervical Canals,Uterine Cervical Canals
D003094 Collagen A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH). Avicon,Avitene,Collagen Felt,Collagen Fleece,Collagenfleece,Collastat,Dermodress,Microfibril Collagen Hemostat,Pangen,Zyderm,alpha-Collagen,Collagen Hemostat, Microfibril,alpha Collagen
D003239 Connective Tissue Cells A group of cells that includes FIBROBLASTS, cartilage cells, ADIPOCYTES, smooth muscle cells, and bone cells. Cell, Connective Tissue,Cells, Connective Tissue,Connective Tissue Cell
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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