Biomaterial Database

Subcellular localization of the enzyme that forms mannosyl retinyl phosphate from guanosine diphosphate [14C]mannose and retinyl phosphate. 1979

M J Smith, and J B Schreiber, and G Wolf

The subcellular distribution of the enzyme catalysing the conversion of retinyl phosphate and GDP-[14C]mannose into [14C]mannosyl retinyl phosphate was determined by using subcellular fractions of rat liver. Purity of fractions, as determined by marker enzymes, was 80% or better. The amount of mannosyl retinyl phosphate formed (pmol/min per mg of protein) for each fraction was: rough endoplasmic reticulum 0.48 +/- 0.09 (mean +/- S.D.); smooth membranes (consisting of 60% smooth endoplasmic reticulum and 40% Golgi apparatus), 0.18 +/- 0.03; Golgi apparatus, 0.13 +/- 0.03; and plasma membrane 0.02.

UI	MeSH Term	Description	Entries
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D008297	Male		Males
D008360	Mannosephosphates	Phosphoric acid esters of mannose.
D009702	Nucleoside Diphosphate Sugars		Diphosphate Sugars, Nucleoside,Sugars, Nucleoside Diphosphate
D011103	Polyisoprenyl Phosphate Monosaccharides	These compounds function as activated monosaccharide carriers in the biosynthesis of glycoproteins and oligosaccharide phospholipids. Obtained from a nucleoside diphosphate sugar and a polyisoprenyl phosphate.	Isoprenoid Phosphate Monosaccharides,Monosaccharides, Isoprenoid Phosphate,Monosaccharides, Polyisoprenyl Phosphate,Phosphate Monosaccharides, Isoprenoid,Phosphate Monosaccharides, Polyisoprenyl
D011105	Polyisoprenyl Phosphate Sugars	Compounds functioning as activated glycosyl carriers in the biosynthesis of glycoproteins and glycophospholipids. They include the polyisoprenyl pyrophosphates.	Isoprenoid Phosphate Sugars,Sugar Pyrophosphorylpolyprenols,Phosphate Sugars, Isoprenoid,Phosphate Sugars, Polyisoprenyl,Pyrophosphorylpolyprenols, Sugar,Sugars, Isoprenoid Phosphate,Sugars, Polyisoprenyl Phosphate
D011106	Polyisoprenyl Phosphates	Phosphoric or pyrophosphoric acid esters of polyisoprenoids.	Isoprenoid Phosphates,Terpene Phosphates,Phosphates, Isoprenoid,Phosphates, Polyisoprenyl,Phosphates, Terpene
D011506	Proteins	Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.	Gene Products, Protein,Gene Proteins,Protein,Protein Gene Products,Proteins, Gene
D004224	Diterpenes	Twenty-carbon compounds derived from MEVALONIC ACID or deoxyxylulose phosphate.	Diterpene,Diterpenes, Cembrane,Diterpenes, Labdane,Diterpenoid,Labdane Diterpene,Norditerpene,Norditerpenes,Norditerpenoid,Cembranes,Diterpenoids,Labdanes,Norditerpenoids,Cembrane Diterpenes,Diterpene, Labdane,Labdane Diterpenes
D006155	Guanosine Diphosphate Mannose	A nucleoside diphosphate sugar which can be converted to the deoxy sugar GDPfucose, which provides fucose for lipopolysaccharides of bacterial cell walls. Also acts as mannose donor for glycolipid synthesis.	GDP Mannose,Guanosine Diphosphomannose,Guanosine Pyrophosphate Mannose,Diphosphate Mannose, Guanosine,Diphosphomannose, Guanosine,Mannose, GDP,Mannose, Guanosine Diphosphate,Mannose, Guanosine Pyrophosphate,Pyrophosphate Mannose, Guanosine