-transparent.png){kind=logo}
Tobramycin kinetics were examined in 9 morbidly obese women following a single intravenous (120 mg) bolus. After the injection, serum elimination conformed to a 2-compartment open model with alpha and beta t1/2s of 0.285 and 2.1 hr. The volume of distribution (Varea) was determined to be 0.44 1/kg ideal body weight (IBW) and 0.20 1/kg total body weight (TBW). To normalize Varea to 0.26 1/kg, 58% of the patients' adipose weight (TBW -- IBW) must also be taken into account.
Related Publications
R A Blouin, and
H J Mann, and
W O Griffen, and
L A Bauer, and
K E Record
April 1980,
American journal of hospital pharmacy,
R A Blouin, and
H J Mann, and
W O Griffen, and
L A Bauer, and
K E Record
November 2011,
Clinical pharmacokinetics,
R A Blouin, and
H J Mann, and
W O Griffen, and
L A Bauer, and
K E Record
October 2011,
European journal of clinical pharmacology,
R A Blouin, and
H J Mann, and
W O Griffen, and
L A Bauer, and
K E Record
January 1985,
Clinical pharmacy,
R A Blouin, and
H J Mann, and
W O Griffen, and
L A Bauer, and
K E Record
November 1990,
DICP : the annals of pharmacotherapy,
R A Blouin, and
H J Mann, and
W O Griffen, and
L A Bauer, and
K E Record
March 2017,
Journal of clinical pharmacology,
R A Blouin, and
H J Mann, and
W O Griffen, and
L A Bauer, and
K E Record
March 2017,
Antimicrobial agents and chemotherapy,
R A Blouin, and
H J Mann, and
W O Griffen, and
L A Bauer, and
K E Record
August 2015,
The Journal of antimicrobial chemotherapy,
R A Blouin, and
H J Mann, and
W O Griffen, and
L A Bauer, and
K E Record
October 2011,
The Journal of antimicrobial chemotherapy,
R A Blouin, and
H J Mann, and
W O Griffen, and
L A Bauer, and
K E Record
October 2015,
The Journal of antimicrobial chemotherapy,
