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Acrosin immunogen was purified from rabbit testes by sequential acid extraction, ammonium sulfate fractionation, cation-exchange, and affinity chromatography. Twelve females received intradermal injections of purified acrosin in Freund's complete adjuvant followed by a booster injection 6 weeks later. A radioimmunoassay for rabbit acrosin was developed and used to monitor the immune response of the recipients. The females were mated at the time when serum titers of acrosin antibodies were maximal. Four of the animals did not become pregnant, and three of these had the highest antibody titers in the total group. The remaining eight rabbits delivered normal litters at term. Of four control females (immunized with bovine serum albumin), one did not become pregnant. The pregnancy rates for the control and acrosin-immunized rabbits were 75% and 67%, respectively. It is concluded that, although active immunization with acrosin had no significant effect on fertility, the antibody titer produced may be a factor.
F N Syner, and
R Kuras, and
K S Moghissi
January 1979,
Journal of reproductive immunology,
F N Syner, and
R Kuras, and
K S Moghissi
April 1987,
American journal of reproductive immunology and microbiology : AJRIM,
F N Syner, and
R Kuras, and
K S Moghissi
February 1966,
The Journal of endocrinology,
F N Syner, and
R Kuras, and
K S Moghissi
December 1978,
The Journal of endocrinology,
F N Syner, and
R Kuras, and
K S Moghissi
August 1977,
Infection and immunity,
F N Syner, and
R Kuras, and
K S Moghissi
January 2007,
Society of Reproduction and Fertility supplement,
F N Syner, and
R Kuras, and
K S Moghissi
February 1969,
Endocrinology,
F N Syner, and
R Kuras, and
K S Moghissi
December 1981,
The Journal of experimental zoology,
F N Syner, and
R Kuras, and
K S Moghissi
April 1980,
Journal of comparative pathology,
F N Syner, and
R Kuras, and
K S Moghissi
January 1979,
Folia biologica,
