-transparent.png){kind=logo}
The effect of cyproterone acetate (CA) on the pituitary-testicular axis was studied in 6 healthy men. A dose of 300 mg of CA was administered orally in the early morning, after 3 h blood samples were collected using a multiple sample technique. Testosterone (T) levels were decreased by CA in all subjects (p 0.01), LH in all (p less than 0.01) but one whereas 17-hydroxyprogesterone did not show any significant variation. In vitro, using an equilibrium dialysis, CA displaced T from plasma-binding proteins in males at 37 degrees C. The role of testosterone-binding globulin on the effects of CA on the pituitary-testicular axis remains to be clarified.
Related Publications
R D'Agata, and
S Gulizia, and
E Vicari, and
A Aliffi, and
P Polosa
February 1978,
Acta endocrinologica,
R D'Agata, and
S Gulizia, and
E Vicari, and
A Aliffi, and
P Polosa
November 1984,
The Journal of clinical endocrinology and metabolism,
R D'Agata, and
S Gulizia, and
E Vicari, and
A Aliffi, and
P Polosa
May 1973,
Endokrinologie,
R D'Agata, and
S Gulizia, and
E Vicari, and
A Aliffi, and
P Polosa
January 1981,
Acta endocrinologica,
R D'Agata, and
S Gulizia, and
E Vicari, and
A Aliffi, and
P Polosa
December 1982,
British journal of obstetrics and gynaecology,
R D'Agata, and
S Gulizia, and
E Vicari, and
A Aliffi, and
P Polosa
May 1982,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
R D'Agata, and
S Gulizia, and
E Vicari, and
A Aliffi, and
P Polosa
January 1993,
Andrologia,
R D'Agata, and
S Gulizia, and
E Vicari, and
A Aliffi, and
P Polosa
October 2002,
International journal of andrology,
R D'Agata, and
S Gulizia, and
E Vicari, and
A Aliffi, and
P Polosa
May 1976,
The Journal of clinical endocrinology and metabolism,
R D'Agata, and
S Gulizia, and
E Vicari, and
A Aliffi, and
P Polosa
November 1980,
Journal of reproduction and fertility,
