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The changes of myospherulosis were observed in masses from the buttocks of three patients. Ultrastructural examination of parent bodies and spherules from two patients revealed some spherules to contain dense bodies and filaments. Spherules had a double electron dense wall: the outer layer had a thickness corresponding to that of a cell membrane. Incubation of packed red blood cells with tetracycline ointment produced a similar electron dense deposit on the inner aspect of the cell membrane of the erythrocytes. No filaments or parent bodies were seen. Our findings support the hypothesis that myospherulosis represents altered red blood cells. The filaments seen in our patients may represent polymers of haemoglobin. It is suggested that parent bodies may be derived from histiocytes.
A G Rose, and
A H Timme, and
S K Price, and
M Emms, and
J Dale
May 1980,
American journal of clinical pathology,
A G Rose, and
A H Timme, and
S K Price, and
M Emms, and
J Dale
March 1968,
Journal of cell science,
A G Rose, and
A H Timme, and
S K Price, and
M Emms, and
J Dale
July 1992,
Molecular reproduction and development,
A G Rose, and
A H Timme, and
S K Price, and
M Emms, and
J Dale
August 1982,
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons,
A G Rose, and
A H Timme, and
S K Price, and
M Emms, and
J Dale
August 2013,
Annals of diagnostic pathology,
A G Rose, and
A H Timme, and
S K Price, and
M Emms, and
J Dale
February 1985,
The Nebraska medical journal,
A G Rose, and
A H Timme, and
S K Price, and
M Emms, and
J Dale
January 1979,
American journal of clinical pathology,
A G Rose, and
A H Timme, and
S K Price, and
M Emms, and
J Dale
April 1979,
Southern medical journal,
A G Rose, and
A H Timme, and
S K Price, and
M Emms, and
J Dale
August 1979,
Clinical otolaryngology and allied sciences,
A G Rose, and
A H Timme, and
S K Price, and
M Emms, and
J Dale
July 1995,
Human pathology,
