Synthesis of analogs of the serum thymic nonapeptide, "facteur thymique serique" (FTS). Part I. 1979

D Blanot, and J Martinez, and G Auger, and E Bricas

Analogs of FTS (Facteur Thymique Sérique), less than :formula: (see text), a circulating thymic factor, were prepared by replacing the amino acid residues in positions 1, 2, 8 and 9, or by shortening the nonapeptide chain at the N- or C-terminal end. These peptides were synthesized by two different schemes using the conventional synthesis in solution.

UI MeSH Term Description Entries
D010446 Peptide Fragments Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques. Peptide Fragment,Fragment, Peptide,Fragments, Peptide
D000595 Amino Acid Sequence The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION. Protein Structure, Primary,Amino Acid Sequences,Sequence, Amino Acid,Sequences, Amino Acid,Primary Protein Structure,Primary Protein Structures,Protein Structures, Primary,Structure, Primary Protein,Structures, Primary Protein
D000596 Amino Acids Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins. Amino Acid,Acid, Amino,Acids, Amino
D013935 Thymic Factor, Circulating A thymus-dependent nonapeptide found in normal blood. Stimulates the formation of E rosettes and is believed to be involved in T-cell differentiation. Facteur Thymique Serique,Serum Thymic Factor,Circulating Factor, Thymic,Factor, Thymic Circulating,Nonathymulin,Thymic Serum Factor,Thymulin,Thymuline,Circulating Thymic Factor,Factor, Circulating Thymic,Factor, Serum Thymic,Factor, Thymic Serum,Serique, Facteur Thymique,Serum Factor, Thymic,Thymic Circulating Factor,Thymic Factor, Serum,Thymique Serique, Facteur
D013951 Thymus Hormones Humoral factors secreted by the thymus gland. They participate in the development of the lymphoid system and the maturation of the cellular immune response. Thymic Hormones,Hormones, Thymic,Hormones, Thymus

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