Comparative bioavailability and pharmacokinetics of sotalol administered alone and in combination with hydrochlorothiazide.
1979
H Sundquist, and
M Anttila, and
A Simon, and
J W Reich
UI
MeSH Term
Description
Entries
D007700
Kinetics
The rate dynamics in chemical or physical systems.
D008297
Male
Males
D008875
Middle Aged
An adult aged 45 - 64 years.
Middle Age
D004347
Drug Interactions
The action of a drug that may affect the activity, metabolism, or toxicity of another drug.
Drug Interaction,Interaction, Drug,Interactions, Drug
D005260
Female
Females
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006852
Hydrochlorothiazide
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.
Adults
D013015
Sotalol
An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.