Biomaterial Database

[Fluorescein angiography of the optic disc in ocular hypertension and glaucoma (author's transl)]. 1979

M Bonnet, and T Baserer, and J D Grange

A fluorescein angiography of the optic disc has been performed on 62 eyes in 41 patients suffering from ocular hypertension or glaucoma. The angiogram was abnormal in 32 eyes. 11 eyes showed an absolute hypofluorescence involving the whole optic disc. 15 eyes showed an absolute hypofluorescence limited to a part of the cup and the rim. 6 eyes showed a late hyperfluorescence of the fundus of the cup. Total hypofluorescence throughout all phases of fluorescein angiogram corresponds to filling defects. Absolute hypofluorescence involving the whole optic disc is associated with visual field loss in all cases. Absolute hypofluorescence involving only an area of the optic disc is associated with a normal visual field in a few cases. It is postulated that the limited filling defects without visual fields defects may be an indication of impending loss of the visual field. Therefore fluorescein angiography could be helpful in clinical assessment of visual prognosis of chronic ocular hypertension and glaucoma. Nevertheless wider experience and followup are necessary to confirm the value of the method.

UI	MeSH Term	Description	Entries
D007429	Intraocular Pressure	The pressure of the fluids in the eye.	Ocular Tension,Intraocular Pressures,Ocular Tensions,Pressure, Intraocular,Pressures, Intraocular,Tension, Ocular,Tensions, Ocular
D009898	Optic Disk	The portion of the optic nerve seen in the fundus with the ophthalmoscope. It is formed by the meeting of all the retinal ganglion cell axons as they enter the optic nerve.	Blind Spot,Optic Disc,Optic Nerve Head,Optic Papilla,Blind Spots,Disc, Optic,Disk, Optic,Head, Optic Nerve,Nerve Head, Optic,Optic Discs,Optic Disks,Optic Nerve Heads,Optic Papillas,Papilla, Optic,Papillas, Optic,Spot, Blind
D005451	Fluorescein Angiography	Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.	Fluorescence Angiography,Fundus Fluorescence Photography,Angiography, Fluorescein,Angiography, Fluorescence,Fluorescence Photography, Fundus,Photography, Fundus Fluorescence
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D005901	Glaucoma	An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)	Glaucomas
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014794	Visual Fields	The total area or space visible in a person's peripheral vision with the eye looking straightforward.	Field, Visual,Fields, Visual,Visual Field