Biomaterial Database

Carcass deposition of dietary long-chain odd carbon fatty acids by rats and their effect on plasma glucose and ketone bodies during starvation. 1979

R L Anderson, and R A Volpenhein

Weanling rats were fed diets containing various levels (0 to 40% of total dietary acids) of long chain, odd-carbon fatty acids (OCFA, 15:0 + 17:0) for 5 weeks. The OCFA did not significantly alter growth or feed efficiency and the OCFA were deposited in the carcass fat in proportion to their concentration in the diet fat. After the 5-week ingestion period, the rats were starved for 48 hours and the effect of carcass OCFA content on weight loss, fat loss, urinary total nitrogen, plasma glucose concentration and plasma ketone body concentrations was determined as a function of starvation time. The results demonstrate that OCFA catabolism during starvation results in a dose related increase in plasma glucose and dose related decrease in plasma ketone bodies without significantly altering the total weight loss, carcass fat loss, or urinary total nitrogen. Finally, the carcass percentage of OCFA did not change during starvation showing that these acids are as readily lost from the carcass during starvation as even chain fatty acids.

UI	MeSH Term	Description	Entries
D007657	Ketone Bodies	The metabolic substances ACETONE; 3-HYDROXYBUTYRIC ACID; and acetoacetic acid (ACETOACETATES). They are produced in the liver and kidney during FATTY ACIDS oxidation and used as a source of energy by the heart, muscle and brain.	Acetone Bodies,Bodies, Acetone,Bodies, Ketone
D008297	Male		Males
D001786	Blood Glucose	Glucose in blood.	Blood Sugar,Glucose, Blood,Sugar, Blood
D001823	Body Composition	The relative amounts of various components in the body, such as percentage of body fat.	Body Compositions,Composition, Body,Compositions, Body
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D004041	Dietary Fats	Fats present in food, especially in animal products such as meat, meat products, butter, ghee. They are present in lower amounts in nuts, seeds, and avocados.	Fats, Dietary,Dietary Fat,Fat, Dietary
D004305	Dose-Response Relationship, Drug	The relationship between the dose of an administered drug and the response of the organism to the drug.	Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D005227	Fatty Acids	Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)	Aliphatic Acid,Esterified Fatty Acid,Fatty Acid,Fatty Acids, Esterified,Fatty Acids, Saturated,Saturated Fatty Acid,Aliphatic Acids,Acid, Aliphatic,Acid, Esterified Fatty,Acid, Saturated Fatty,Esterified Fatty Acids,Fatty Acid, Esterified,Fatty Acid, Saturated,Saturated Fatty Acids
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013217	Starvation	Lengthy and continuous deprivation of food. (Stedman, 25th ed)