Biomaterial Database

Effect of pH on in vitro phagocytosis of Streptococcus pyogenes. 1969

A Beck, and S Bergner-Rabinowitz, and I Ofek

Phagocytosis experiments were performed with mouse peritoneal leucocytes (MPL). The natural pH of the mouse peritoneal cavity was found to be between 6.1 and 6.3. The phagocytic and intracellular killing activities of MPL by pH variations was studied. It was observed that the optimal ingestion and intracellular killing of bacteria is at the natural pH of the peritoneal cavity.

UI	MeSH Term	Description	Entries
D007962	Leukocytes	White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES).	Blood Cells, White,Blood Corpuscles, White,White Blood Cells,White Blood Corpuscles,Blood Cell, White,Blood Corpuscle, White,Corpuscle, White Blood,Corpuscles, White Blood,Leukocyte,White Blood Cell,White Blood Corpuscle
D008297	Male		Males
D010529	Peritoneal Cavity	The space enclosed by the peritoneum. It is divided into two portions, the greater sac and the lesser sac or omental bursa, which lies behind the STOMACH. The two sacs are connected by the foramen of Winslow, or epiploic foramen.	Greater Sac,Lesser Sac,Omental Bursa,Bursa, Omental,Cavity, Peritoneal,Sac, Greater,Sac, Lesser
D010587	Phagocytosis	The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).	Phagocytoses
D005260	Female		Females
D006863	Hydrogen-Ion Concentration	The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH	pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013297	Streptococcus pyogenes	A species of gram-positive, coccoid bacteria isolated from skin lesions, blood, inflammatory exudates, and the upper respiratory tract of humans. It is a group A hemolytic Streptococcus that can cause SCARLET FEVER and RHEUMATIC FEVER.	Flesh-Eating Bacteria,Streptococcus Group A,Bacteria, Flesh-Eating
D051379	Mice	The common name for the genus Mus.	Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus

Related Publications

A Beck, and S Bergner-Rabinowitz, and I Ofek

EFFECT OF PARTIALLY PURIFIED STREPTOCOCCAL M PROTEIN ON THE IN VITRO PHAGOCYTOSIS OF STREPTOCOCCUS PYOGENES.

March 1965, Journal of bacteriology,

A Beck, and S Bergner-Rabinowitz, and I Ofek

The role of M protein in phagocytosis. II. Opsonization of Streptococcus pyogenes in vitro.

October 1979, Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie,

A Beck, and S Bergner-Rabinowitz, and I Ofek

MicroRNA fragments derived from Streptococcus pyogenes enable activation of neutrophil phagocytosis: in vitro study.

March 2013, Microbes and infection,

A Beck, and S Bergner-Rabinowitz, and I Ofek

Protein F1 and Streptococcus pyogenes resistance to phagocytosis.

June 2007, Infection and immunity,

A Beck, and S Bergner-Rabinowitz, and I Ofek

The effect of pH on the fermentation of glucose and galactose by Streptococcus pyogenes.

July 1955, Journal of bacteriology,

A Beck, and S Bergner-Rabinowitz, and I Ofek

Effect of Streptococcus pyogenes on tissue cells.

June 1967, Journal of bacteriology,