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Variants of Serratia marcescens induced by freeze-drying. 1969

M Servín-Massieu, and R Cruz-Camarillo

Unusually high numbers of pigmentless variants and sectored colonies in cultures of lyophylized Serratia marcescens are reported. Clonal analyses of sectored colonies show the presence of unstable bacteria that continue to sector again when plated. Further analysis of pigmentless variants suggest that pigment formation, oxygen uptake, and the production of an inducible protease are affected.

UI MeSH Term Description Entries
D010860 Pigments, Biological Any normal or abnormal coloring matter in PLANTS; ANIMALS or micro-organisms. Biological Pigments
D005612 Freeze Drying Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products. Lyophilization,Drying, Freeze,Dryings, Freeze,Freeze Dryings,Lyophilizations
D012706 Serratia marcescens A species of gram-negative, facultatively anaerobic, rod-shaped bacteria found in soil, water, food, and clinical specimens. It is a prominent opportunistic pathogen for hospitalized patients.
D014644 Genetic Variation Genotypic differences observed among individuals in a population. Genetic Diversity,Variation, Genetic,Diversity, Genetic,Diversities, Genetic,Genetic Diversities,Genetic Variations,Variations, Genetic

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