Biomaterial Database

Dermatoglyphic findings in Rubinstein-Taybi syndrome. 1979

M Atasu

The dermatoglyphics of seven patients with Rubinstein-Taybi syndrome and their seventeen family members were compared with those of 250 male and 250 female controls. The most striking dermatoglyphic findings of the patients were the increased frequency of arches, decreased frequency of ulnar loops and reduced ridge-counts on the finger-tips, particularly on the thumbs, lower a-b ridge-counts, increased frequency of I, Ir, II loops, e, f, and t'' triradii, decreased frequency of H loops and tb triradii on the palms, increased frequency of If loops, decreased frequency of I loops, f and p triradii on the soles. The relatives of the patients had more radial loops on the finger-tips, I and Hr loops and t' triradii on the palms, II, III, loops, f and z triradii on the soles.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D010641	Phenotype	The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.	Phenotypes
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D003878	Dermatoglyphics	The study of the patterns of ridges of the skin of the fingers, palms, toes, and soles.	Fingerprints,Plantar Prints,Fingerprint,Plantar Print,Print, Plantar,Prints, Plantar
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000015	Abnormalities, Multiple	Congenital abnormalities that affect more than one organ or body structure.	Multiple Abnormalities
D012415	Rubinstein-Taybi Syndrome	A chromosomal disorder characterized by MENTAL RETARDATION, broad thumbs, webbing of fingers and toes, beaked nose, short upper lip, pouting lower lip, agenesis of corpus callosum, large foramen magnum, keloid formation, pulmonary stenosis, vertebral anomalies, chest wall anomalies, sleep apnea, and megacolon. The disease has an autosomal dominant pattern of inheritance and is associated with deletions of the short arm of chromosome 16 (16p13.3).	Broad Thumb-Hallux Syndrome,Broad Thumbs and Great Toes, Characteristic Facies, and Mental Retardation,Rubinstein Syndrome,Broad Thumb Hallux Syndrome,Broad Thumb-Hallux Syndromes,Rubinstein Taybi Syndrome,Syndrome, Broad Thumb-Hallux,Syndrome, Rubinstein,Syndrome, Rubinstein-Taybi,Syndromes, Broad Thumb-Hallux