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Clinical-functional analysis of the efficacy of propranolol was conducted in 32 patients with ischemic heart disease and stable angina pectoris (with angiographically verified stenosing coronary atherosclerosis) depending on the initial myocardial contractility. A marked antianginal effect of propranolol in a dose of up to 160 mg daily was demonstrated irrespective of the initial myocardial contractile function. Treatment with propranolol was not attended with signs of cardiac insufficiency or aggravation of its subclinical symptoms. The results of the study provide convincing data that optimum doses of blocking agents of beta-adrenergic receptors of the myocardium causing a negative inotropic effect even in patients with diminished myocardial function may be used more widely.
B A Sidorenko, and
L V Kasatkina, and
V P Lupanov, and
V P Mazaev
May 2001,
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
B A Sidorenko, and
L V Kasatkina, and
V P Lupanov, and
V P Mazaev
February 1990,
Vrachebnoe delo,
B A Sidorenko, and
L V Kasatkina, and
V P Lupanov, and
V P Mazaev
April 1980,
Journal of pharmaceutical sciences,
B A Sidorenko, and
L V Kasatkina, and
V P Lupanov, and
V P Mazaev
January 1984,
The Journal of cardiovascular surgery,
B A Sidorenko, and
L V Kasatkina, and
V P Lupanov, and
V P Mazaev
January 1996,
Patologicheskaia fiziologiia i eksperimental'naia terapiia,
B A Sidorenko, and
L V Kasatkina, and
V P Lupanov, and
V P Mazaev
January 1986,
Sovetskaia meditsina,
B A Sidorenko, and
L V Kasatkina, and
V P Lupanov, and
V P Mazaev
January 1978,
Progress in cardiovascular diseases,
B A Sidorenko, and
L V Kasatkina, and
V P Lupanov, and
V P Mazaev
May 1983,
Kokyu to junkan. Respiration & circulation,
B A Sidorenko, and
L V Kasatkina, and
V P Lupanov, and
V P Mazaev
January 1973,
The Journal of cardiovascular surgery,
B A Sidorenko, and
L V Kasatkina, and
V P Lupanov, and
V P Mazaev
May 1981,
Vrachebnoe delo,
