Biomaterial Database

[Clinico-morphological comparisons of autoimmune processes in the thyroid gland in the endemic goiter region]. 1979

I D Levit

A total of 2558 patients (95% of patients who sustained strumectomy in the Chelyabinsk region in 1969--1977 for euthyroid nodular goiter) were examined. There proved to be a relationship between the iodine content in the food products of the population and the frequency of the morphologically-definable autoimmune processes in the thyroid gland; this dependence was direct for the marked autoaggression processes, and indirect--for the initial ones. This dependence is also confirmed by a rare combination of multinodular goiter with diffuse autoimmune thyroiditis and a frequent one--with the initial autoaggression forms.

UI	MeSH Term	Description	Entries
D007455	Iodine	A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.	Iodine-127,Iodine 127
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D005260	Female		Females
D006043	Goiter, Endemic	A form of IODINE deficiency disorders characterized by an enlargement of the THYROID GLAND in a significantly large fraction of a POPULATION GROUP. Endemic goiter is common in mountainous and iodine-deficient areas of the world where the DIET contains insufficient amount of iodine.	Endemic Goiter,Endemic Goiters,Goiters, Endemic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001327	Autoimmune Diseases	Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.	Autoimmune Disease,Disease, Autoimmune,Diseases, Autoimmune
D012800	Siberia	A region, north-central Asia, largely in Russia. It extends from the Ural Mountains to the Pacific Ocean and from the Arctic Ocean to central Kazakhstan and the borders of China and Mongolia.	Russian S.F.S.R., Asian,Russian Federation (Asia)
D013961	Thyroid Gland	A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.	Thyroid,Gland, Thyroid,Glands, Thyroid,Thyroid Glands,Thyroids