Quantitation of circulating fibrinogen breakdown products in intravascular clotting.
1966
H C Hemker, and
N Fekkes, and
A Hensen, and
H Schrijver, and
E A Loeliger
UI
MeSH Term
Description
Entries
D005340
Fibrinogen
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
Coagulation Factor I,Factor I,Blood Coagulation Factor I,gamma-Fibrinogen,Factor I, Coagulation,gamma Fibrinogen
D013927
Thrombosis
Formation and development of a thrombus or blood clot in BLOOD VESSELS.