Analysis of ethylene oxide--worker exposure. 1979

S J Romano, and J A Renner

A personal air sampling method for assessing individual worker exposure to ethylene oxide has been developed. The method is based on trapping ethylene oxide in dilute sulfuric acid where it is converted to ethylene glycol. The ethylene glycol is determined by gas chromatography using a glass column packed with 5% Igepal CO-990 on Teflon T-6. This column produces linear calibration curves and symmetrical peaks. The method has been shown to recover 94.2% ethylene oxide in the 1 to 8 ppm concentration range. The sampling technique is independent of flow and sample size. Advantages over the NIOSH method are discussed.

UI MeSH Term Description Entries
D009787 Occupational Medicine Medical specialty concerned with the promotion and maintenance of the physical and mental health of employees in occupational settings. Industrial Medicine,Medicine, Industrial,Medicine, Occupational
D002849 Chromatography, Gas Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix. Chromatography, Gas-Liquid,Gas Chromatography,Chromatographies, Gas,Chromatographies, Gas-Liquid,Chromatography, Gas Liquid,Gas Chromatographies,Gas-Liquid Chromatographies,Gas-Liquid Chromatography
D004781 Environmental Exposure The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals. Exposure, Environmental,Environmental Exposures,Exposures, Environmental
D005027 Ethylene Oxide A colorless and flammable gas at room temperature and pressure. Ethylene oxide is a bactericidal, fungicidal, and sporicidal disinfectant. It is effective against most micro-organisms, including viruses. It is used as a fumigant for foodstuffs and textiles and as an agent for the gaseous sterilization of heat-labile pharmaceutical and surgical materials. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p794) Oxirane,Oxide, Ethylene
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000393 Air Pollutants Any substance in the air which could, if present in high enough concentration, harm humans, animals, vegetation or materials. Substances include GASES; PARTICULATE MATTER; and volatile ORGANIC CHEMICALS. Air Pollutant,Air Pollutants, Environmental,Environmental Air Pollutants,Environmental Pollutants, Air,Air Environmental Pollutants,Pollutant, Air,Pollutants, Air,Pollutants, Air Environmental,Pollutants, Environmental Air
D000395 Air Pollutants, Occupational Toxic air-borne matter related to work performed They are usually produced by the specific nature of the occupation. Occupational Air Pollutants,Pollutants, Occupational Air

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