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The results of treatment of 16 cases of alopecia areata with dinitrochlorobenzene (D.N.C.B.) are reported. The chemical is applied to the scalp once a week, beginning three weeks after sensitivation (patch-test 1/50). We have available to us a battery of D.N.C.B. solutions of various concentrations (11 solutions ranging from 1/20,000 to 1/25). The concentration used varies at each application with the desired result being a contact dermatitis. In the 16 cases studied, 4 were classified as good results, 8 as poor and 4 as failures. Hairgrowth begins with three weeks following the first D.N.C.B. application to the scalp. Good prognostic signs include the facility in sensitizing the patient as well as the intensity of this reaction. The reasons for this treatment's efficacy being as yet unknown, the standardization, as well as the actual technique are, at the present time difficult and hazardous.
Y De Prost, and
F R Paquez, and
R Touraine
November 1977,
Lancet (London, England),
Y De Prost, and
F R Paquez, and
R Touraine
November 1980,
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology,
Y De Prost, and
F R Paquez, and
R Touraine
March 1982,
Zeitschrift fur Hautkrankheiten,
Y De Prost, and
F R Paquez, and
R Touraine
December 1979,
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology,
Y De Prost, and
F R Paquez, and
R Touraine
January 1980,
Dermatologica,
Y De Prost, and
F R Paquez, and
R Touraine
February 1981,
Wiener klinische Wochenschrift,
Y De Prost, and
F R Paquez, and
R Touraine
January 1978,
Annales de dermatologie et de venereologie,
Y De Prost, and
F R Paquez, and
R Touraine
June 1981,
Dermatologische Monatschrift,
Y De Prost, and
F R Paquez, and
R Touraine
January 2001,
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi,
Y De Prost, and
F R Paquez, and
R Touraine
September 1981,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
