BIOMAT Database Logo BIOMAT Database Logo

Biliary excretion of erythromycin after parenteral administration. 1979

P Chelvan, and J M Hamilton-Miller, and W Brumfitt

1 The biliary excretion of erythromycin has been studied following parenteral administration in 23 patients. 2 Mean bile levels of the drug were approximately ten times higher than corresponding serum concentrations 1 h after i.v. (erythromycin lactobionate) and i.m. (erythromycin ethylsuccinate) injection. 3 Thus, unlike many antimicrobial agents, these compounds are well concentrated in the bile.

UI MeSH Term Description Entries
D007273 Injections, Intramuscular Forceful administration into a muscle of liquid medication, nutrient, or other fluid through a hollow needle piercing the muscle and any tissue covering it. Intramuscular Injections,Injection, Intramuscular,Intramuscular Injection
D007275 Injections, Intravenous Injections made into a vein for therapeutic or experimental purposes. Intravenous Injections,Injection, Intravenous,Intravenous Injection
D004917 Erythromycin A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. Erycette,Erymax,Erythromycin A,Erythromycin C,Erythromycin Lactate,Erythromycin Phosphate,Ilotycin,T-Stat,Lactate, Erythromycin,Phosphate, Erythromycin,T Stat,TStat
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001646 Bile An emulsifying agent produced in the LIVER and secreted into the DUODENUM. Its composition includes BILE ACIDS AND SALTS; CHOLESTEROL; and ELECTROLYTES. It aids DIGESTION of fats in the duodenum. Biliary Sludge,Sludge, Biliary
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

Related Publications

P Chelvan, and J M Hamilton-Miller, and W Brumfitt
[Renal and biliary excretion of biligraffin after various modes of parenteral administration].
December 1955, Arztliche Wochenschrift,
P Chelvan, and J M Hamilton-Miller, and W Brumfitt
Increased biliary transferrin excretion following parenteral aluminium administration to rats.
June 1993, Pharmacology & toxicology,
P Chelvan, and J M Hamilton-Miller, and W Brumfitt
The biliary excretion of erythromycin (ilotycin).
March 1956, Surgery, gynecology & obstetrics,
P Chelvan, and J M Hamilton-Miller, and W Brumfitt
Excretion of erythromycin through the biliary tract.
October 1955, Antibiotic medicine & clinical therapy (New York, NY),
P Chelvan, and J M Hamilton-Miller, and W Brumfitt
[Erythromycin-ascorbinate--a drug for parenteral administration].
January 1966, Antibiotiki,
P Chelvan, and J M Hamilton-Miller, and W Brumfitt
Biliary excretion kinetics of phenolphthalein glucuronide after intravenous and retrograde biliary administration.
December 1974, The Journal of pharmacy and pharmacology,
P Chelvan, and J M Hamilton-Miller, and W Brumfitt
[Excretion of amino acid nitrogen after parenteral administration of casein hydrolysate].
May 1955, Ceskoslovenska pediatrie,
P Chelvan, and J M Hamilton-Miller, and W Brumfitt
Biliary excretion of polystyrene microspheres with covalently linked FITC fluorescence after oral and parenteral administration to male Wistar rats.
January 1996, Journal of drug targeting,
P Chelvan, and J M Hamilton-Miller, and W Brumfitt
[Renal excretion of trihydroxy-ethylrutoside (Venoruton) after parenteral and oral administration].
June 1970, Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete,
P Chelvan, and J M Hamilton-Miller, and W Brumfitt
[Urinary excretion of riboflavin after its parenteral administration in normal & premature infants].
June 1957, La Clinica pediatrica,
Copied contents to your clipboard!