Cytochemical studies on the origin of bizarre, acid phosphatase-rich structures in rat liver cells.
1970
A Vorbrodt, and
S Krzyzowska-Gruca, and
S Gruca, and
W Bartoszewicz
UI
MeSH Term
Description
Entries
D003609
Dactinomycin
A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)
The decrease in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.
Chemical Depression,Chemical Depressions,Depressions, Chemical
D000135
Acid Phosphatase
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.
Animal,Metazoa,Animalia
Related Publications
A Vorbrodt, and
S Krzyzowska-Gruca, and
S Gruca, and
W Bartoszewicz