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Twenty-one patients, each having at least one metastasis per lung were investigated. A single dose of 1000 rad was delivered to the metastasis located in one lung. while the metastasis located in the other lung received 2 doses of 500 rad separated by a 3-hour interval. The changes in volume of the irradiated metastases were followed at least until the metastases reattained their initial volume. By comparing in each patient the effects of the 2 types of exposure it was possible to estimate the extrapolation number, n, of the survival curve of the tumour cells. In spite of many sources of inaccuracies, it seems possible to conclude that n is not very high, probably smaller than in many normal tissues.Furthermore this work demonstrated, in practically all the tumours studied, an acceleration of the growth rate of the metastases after irradiation.
E P Malaise, and
A Charbit, and
N Chavaudra, and
P F Combes, and
J Douchez, and
M Tubiana
January 1984,
The British journal of cancer. Supplement,
E P Malaise, and
A Charbit, and
N Chavaudra, and
P F Combes, and
J Douchez, and
M Tubiana
November 1980,
International journal of radiation biology and related studies in physics, chemistry, and medicine,
E P Malaise, and
A Charbit, and
N Chavaudra, and
P F Combes, and
J Douchez, and
M Tubiana
January 1991,
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine,
E P Malaise, and
A Charbit, and
N Chavaudra, and
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M Tubiana
January 1979,
Radiation research,
E P Malaise, and
A Charbit, and
N Chavaudra, and
P F Combes, and
J Douchez, and
M Tubiana
February 1981,
International journal of radiation biology and related studies in physics, chemistry, and medicine,
E P Malaise, and
A Charbit, and
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P F Combes, and
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November 1985,
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E P Malaise, and
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June 1987,
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E P Malaise, and
A Charbit, and
N Chavaudra, and
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M Tubiana
June 2018,
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E P Malaise, and
A Charbit, and
N Chavaudra, and
P F Combes, and
J Douchez, and
M Tubiana
December 1982,
Radiation research,
E P Malaise, and
A Charbit, and
N Chavaudra, and
P F Combes, and
J Douchez, and
M Tubiana
March 1979,
International journal of radiation oncology, biology, physics,
