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Fate of androsta-4,16-dien-3-one and the origin of 3 -hydroxy-5 -androst-16-ene in man. 1972

B W Brooksbank, and D A Wilson, and D A MacSweeney

UI MeSH Term Description Entries
D007659 Ketones Organic compounds containing a carbonyl group Ketone
D008055 Lipids A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed) Lipid
D008297 Male Males
D008657 Metabolic Clearance Rate Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site. Total Body Clearance Rate,Clearance Rate, Metabolic,Clearance Rates, Metabolic,Metabolic Clearance Rates,Rate, Metabolic Clearance,Rates, Metabolic Clearance
D002247 Carbon Isotopes Stable carbon atoms that have the same atomic number as the element carbon but differ in atomic weight. C-13 is a stable carbon isotope. Carbon Isotope,Isotope, Carbon,Isotopes, Carbon
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000731 Androstanes The family of steroids from which the androgens are derived.
D001365 Axilla Area of the human body underneath the SHOULDER JOINT, also known as the armpit or underarm. Armpit,Underarm

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B W Brooksbank, and D A Wilson, and D A MacSweeney
Isolation and identification of 3 -hydroxy-5 -androst-16-ene and 5 -androst-16-en-3-one from procine adipose tissue.
September 1971, The Journal of endocrinology,
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Proceedings: Studies on the metabolism of the odoriferous ketones, 5alpha-androst-16-en-3-one and androsta-4,16-dien-3-one, by the nasal epithelium of the mature and immature sow.
November 1973, The Journal of endocrinology,
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Androsta-4,16-diene-3,6-dione: an unknown member among the smelling androst-16-enes.
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Development of a radioimmunoassay for 5-alpha-androst-16-ene-3-one.
July 1973, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
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[16-oxygenated steroids. Synthesis of 3 beta-hydroxy-androst-5-en-16-one].
December 1967, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
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The identification of 17 alpha-hydroxy-17 beta-methyl-androsta-1,4-dien-3-one as a metabolite of 17 beta-hydroxy-17 alpha-methylandrosta-1,4-dien-3-one in man.
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Anti-tumour effects and pharmacokinetic profile of 17-(5'-isoxazolyl)androsta-4,16-dien-3-one (L-39) in mice: an inhibitor of androgen synthesis.
July 2000, British journal of cancer,
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[Synthesis of mammalian pheromone 5 alpha-androst-16-en-3-one and 5 alpha-Androst-16-en-3 alpha-ol].
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The obligatory intermediacy of 16,17 alpha- and 16,17 beta-epoxides in the biotransformation of androsta-5,16-dien-3 beta-ol to androst-5-ene-3 beta, 16 alpha, 17 beta- and -3 beta, 16 beta, 17 alpha-triols by male rat liver microsomes.
July 1985, The Journal of biological chemistry,
B W Brooksbank, and D A Wilson, and D A MacSweeney
The estimation of 3 alpha-hydroxy-5 alpha-androst-16-ene and other C19-delta 16-steroids in urine by gas-liquid chromatography.
January 1970, Acta endocrinologica,
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