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Hepatic cells in rats were evaluated after subtotal hepatectomy using scintillation scanning with technetium sulfur colloid (TSC), autoradiography, and microstereology techniques. The ability of the liver to accumulate TSC increased during the course of the regeneration as did the labeling of Kupffer and parenchymal cells with tritiated thymidine (3H-tdR). Kupffer to parenchymal cell number ratios and Kupffer cell relative areas were also elevated, attaining peak values at 72 hours post-hepatectomy. This period corresponds to the time of peak erythropoietin (Ep) production in rats with regenerating livers after nephrectomy and exposure to hypoxia. These findings suggest that the Kupffer cell may function as a cellular site of Ep formation.
B A Naughton, and
D J Birnbach, and
P Liu, and
G A Kolks, and
M Z Tung, and
J A Piliero, and
S J Piliero, and
A S Gordon
November 1985,
Journal of surgical oncology,
B A Naughton, and
D J Birnbach, and
P Liu, and
G A Kolks, and
M Z Tung, and
J A Piliero, and
S J Piliero, and
A S Gordon
February 1971,
Vnitrni lekarstvi,
B A Naughton, and
D J Birnbach, and
P Liu, and
G A Kolks, and
M Z Tung, and
J A Piliero, and
S J Piliero, and
A S Gordon
January 1976,
Advances in experimental medicine and biology,
B A Naughton, and
D J Birnbach, and
P Liu, and
G A Kolks, and
M Z Tung, and
J A Piliero, and
S J Piliero, and
A S Gordon
February 1972,
The Johns Hopkins medical journal,
B A Naughton, and
D J Birnbach, and
P Liu, and
G A Kolks, and
M Z Tung, and
J A Piliero, and
S J Piliero, and
A S Gordon
January 1980,
Experimental hematology,
B A Naughton, and
D J Birnbach, and
P Liu, and
G A Kolks, and
M Z Tung, and
J A Piliero, and
S J Piliero, and
A S Gordon
August 1964,
The Journal of clinical investigation,
B A Naughton, and
D J Birnbach, and
P Liu, and
G A Kolks, and
M Z Tung, and
J A Piliero, and
S J Piliero, and
A S Gordon
January 1973,
Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin,
B A Naughton, and
D J Birnbach, and
P Liu, and
G A Kolks, and
M Z Tung, and
J A Piliero, and
S J Piliero, and
A S Gordon
September 1964,
Zentralblatt fur Gynakologie,
B A Naughton, and
D J Birnbach, and
P Liu, and
G A Kolks, and
M Z Tung, and
J A Piliero, and
S J Piliero, and
A S Gordon
December 1971,
Journal of the Reticuloendothelial Society,
B A Naughton, and
D J Birnbach, and
P Liu, and
G A Kolks, and
M Z Tung, and
J A Piliero, and
S J Piliero, and
A S Gordon
September 1970,
Journal of the Reticuloendothelial Society,
