[Treatment of Itsenko-Cushing disease with chlodithane].
1979
E A Vasiukova, and
A M Granovskaia, and
I V Pisarskaia, and
V D Ryzhikov
UI
MeSH Term
Description
Entries
D008939
Mitotane
A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328
Adult
A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.
Adults
Related Publications
E A Vasiukova, and
A M Granovskaia, and
I V Pisarskaia, and
V D Ryzhikov