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A method of measuring regional blood flow (RBF) that is simple in procedure and calculations is described. By arresting flow promptly after a short pulse of diffusible tracer, it is feasible to equate the tracer retained in the tissue (Cfi) with that delivered by the blood. If the arterial pulse is characterized by its mean concentration (Ca) over a known duration (delta t), RBF can be estimated from Cif/Ca delta t). The error involved is relatively small and can be corrected for. If the amount of tracer injected is known, this procedure also provides an estimate of cardiac output and its fractional distribution to the regions sampled. The values obtained for RBF in 4 regions of brain were similar to those previously reported.
A Ames, and
E G Fischer
August 1990,
Nihon Ika Daigaku zasshi,
A Ames, and
E G Fischer
August 1991,
Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics,
A Ames, and
E G Fischer
June 1987,
International journal of radiation oncology, biology, physics,
A Ames, and
E G Fischer
January 1976,
International journal of nuclear medicine and biology,
A Ames, and
E G Fischer
September 1986,
Journal of neuroscience methods,
A Ames, and
E G Fischer
January 1978,
Acta obstetricia et gynecologica Scandinavica,
A Ames, and
E G Fischer
August 1972,
The International journal of applied radiation and isotopes,
A Ames, and
E G Fischer
November 1985,
Postgraduate medicine,
A Ames, and
E G Fischer
January 1996,
Implant dentistry,
A Ames, and
E G Fischer
September 1977,
Physics in medicine and biology,
