BIOMAT Database Logo BIOMAT Database Logo

[In vivo distribution of daunomycin, acetyl kidamycin, actinomycin D and chromomycin A3]. 1971

H Fujita, and T Sawabe, and Y Hanawa, and K Kimura

UI MeSH Term Description Entries
D007275 Injections, Intravenous Injections made into a vein for therapeutic or experimental purposes. Intravenous Injections,Injection, Intravenous,Intravenous Injection
D008297 Male Males
D009374 Neoplasms, Experimental Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms. Experimental Neoplasms,Experimental Neoplasm,Neoplasm, Experimental
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D003609 Dactinomycin A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015) Actinomycin,Actinomycin D,Meractinomycin,Cosmegen,Cosmegen Lyovac,Lyovac-Cosmegen,Lyovac Cosmegen,Lyovac, Cosmegen,LyovacCosmegen
D003630 Daunorubicin A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS. Daunomycin,Rubidomycin,Rubomycin,Cerubidine,Dauno-Rubidomycine,Daunoblastin,Daunoblastine,Daunorubicin Hydrochloride,NSC-82151,Dauno Rubidomycine,Hydrochloride, Daunorubicin,NSC 82151,NSC82151
D004247 DNA A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine). DNA, Double-Stranded,Deoxyribonucleic Acid,ds-DNA,DNA, Double Stranded,Double-Stranded DNA,ds DNA
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000903 Antibiotics, Antineoplastic Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms. Antineoplastic Antibiotics,Cytotoxic Antibiotics,Antibiotics, Cytotoxic
D012313 RNA A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed) RNA, Non-Polyadenylated,Ribonucleic Acid,Gene Products, RNA,Non-Polyadenylated RNA,Acid, Ribonucleic,Non Polyadenylated RNA,RNA Gene Products,RNA, Non Polyadenylated

Related Publications

H Fujita, and T Sawabe, and Y Hanawa, and K Kimura
[THE BINDING OF DAUNOMYCIN, CINERUBIN AND CHROMOMYCIN A3 TO NUCLEIC ACIDS].
February 1965, Biochemische Zeitschrift,
H Fujita, and T Sawabe, and Y Hanawa, and K Kimura
13C-nmr study of chromomycin A3 and actinomycin D complexed with calf thymus DNA fragments.
October 1983, Biopolymers,
H Fujita, and T Sawabe, and Y Hanawa, and K Kimura
A new antitumor antibiotic, kidamycin. IV. Pharmacokinetics of acetyl-kidamycin.
November 1973, The Journal of antibiotics,
H Fujita, and T Sawabe, and Y Hanawa, and K Kimura
A new antitumor antibiotic, kidamycin. 3. Preparation and properties of acetyl kidamycin.
October 1972, The Journal of antibiotics,
H Fujita, and T Sawabe, and Y Hanawa, and K Kimura
Nuclear binding as a determinant of tissue distribution of adriamycin, daunomycin, adriamycinol, daunorubicinol and actinomycin D.
May 1984, Journal of pharmacobio-dynamics,
H Fujita, and T Sawabe, and Y Hanawa, and K Kimura
Interactions of chromomycin A3 and mithramycin with the sequence d(TAGCTAGCTA)2.
January 2001, Indian journal of biochemistry & biophysics,
H Fujita, and T Sawabe, and Y Hanawa, and K Kimura
[Action of chromomycin A3 and of nogalamycin on embryonic cells of the amphibian urodele in in vitro culture. Analogy with the effects of actinomycin D].
December 1967, Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles,
H Fujita, and T Sawabe, and Y Hanawa, and K Kimura
Role of magnesium ion in the interaction between chromomycin A3 and DNA: binding of chromomycin A3-Mg2+ complexes with DNA.
March 1992, Biochemistry,
H Fujita, and T Sawabe, and Y Hanawa, and K Kimura
Biogenesis of chromomycin A3 by Streptomyces griseus.
July 1990, The Journal of antibiotics,
H Fujita, and T Sawabe, and Y Hanawa, and K Kimura
Mechanism of action of chromomycin A3. 3. On the binding of chromomycin A3 with DNA and physiochemical properties of the complex.
May 1968, Journal of biochemistry,
Copied contents to your clipboard!