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One hundred and two patients with clinical signs indicating a possible diagnosis of deep vein thrombosis were studied with the fibrinogen uptake test and phlebography to assess the reliability of the test as a means of diagnosing established venous thrombosis. The test gave a correct diagnosis in 78% of the 85 legs shown to contain thrombus by phlebography and only 19 (10%) false-negative results in the 195 legs examined. The duration of the symptoms, the administration of anticoagulants, and mild leg swelling did not affect the accuracy of the test. Very old thrombus, phlebographically more than 11 days old, was associated with an increased false-negative rate.The fibrinogen uptake test is accurate enough to make it a valuable method of clinical investigation.
N L Browse, and
W F Clapham, and
D N Croft, and
D J Jones, and
M L Thomas, and
J O Williams
February 1972,
Archives of surgery (Chicago, Ill. : 1960),
N L Browse, and
W F Clapham, and
D N Croft, and
D J Jones, and
M L Thomas, and
J O Williams
October 1969,
Acta chirurgica Belgica,
N L Browse, and
W F Clapham, and
D N Croft, and
D J Jones, and
M L Thomas, and
J O Williams
January 1972,
The Milbank Memorial Fund quarterly,
N L Browse, and
W F Clapham, and
D N Croft, and
D J Jones, and
M L Thomas, and
J O Williams
November 1968,
The British journal of surgery,
N L Browse, and
W F Clapham, and
D N Croft, and
D J Jones, and
M L Thomas, and
J O Williams
November 1968,
The British journal of surgery,
N L Browse, and
W F Clapham, and
D N Croft, and
D J Jones, and
M L Thomas, and
J O Williams
December 1974,
Angiology,
N L Browse, and
W F Clapham, and
D N Croft, and
D J Jones, and
M L Thomas, and
J O Williams
March 1970,
Lancet (London, England),
N L Browse, and
W F Clapham, and
D N Croft, and
D J Jones, and
M L Thomas, and
J O Williams
November 1968,
The British journal of surgery,
N L Browse, and
W F Clapham, and
D N Croft, and
D J Jones, and
M L Thomas, and
J O Williams
February 1972,
Archives of surgery (Chicago, Ill. : 1960),
N L Browse, and
W F Clapham, and
D N Croft, and
D J Jones, and
M L Thomas, and
J O Williams
January 1971,
Casopis lekaru ceskych,
