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In NMRI-mice injured with combined lesions (whole-body irradiation with 500 R and, two or seven days later, an open skin wound), lethality increased from 10 or 20% following sole irradiation up to 60%. Investigations of urinary excretion and serum levels in animals with combined injuries did not show undue elevations of the levels of electrolytes, creatinine, urea, uric acid and acid or alkaline equivalents. Analysis of lactate, pyruvate, ATP and ADP in liver tissue and blood serum indicated no significant changes in the energy metabolism in animals with combined injuries in comparison with mice irradiated only. These findings and those of our last communication (24. Mitteilung) seem to be incompatible with the presence of a shock state as cause of the high lethality of mice with combined injuries.
K Lehner, and
K Werdan, and
H Sedlmeier, and
P Zimmer, and
O Messerschmidt
February 1980,
Strahlentherapie,
K Lehner, and
K Werdan, and
H Sedlmeier, and
P Zimmer, and
O Messerschmidt
August 1980,
Strahlentherapie,
K Lehner, and
K Werdan, and
H Sedlmeier, and
P Zimmer, and
O Messerschmidt
December 1979,
Strahlentherapie,
K Lehner, and
K Werdan, and
H Sedlmeier, and
P Zimmer, and
O Messerschmidt
January 1986,
British journal of radiology. Supplement,
K Lehner, and
K Werdan, and
H Sedlmeier, and
P Zimmer, and
O Messerschmidt
May 1970,
Strahlentherapie,
K Lehner, and
K Werdan, and
H Sedlmeier, and
P Zimmer, and
O Messerschmidt
July 1968,
Strahlentherapie,
K Lehner, and
K Werdan, and
H Sedlmeier, and
P Zimmer, and
O Messerschmidt
November 1966,
Strahlentherapie,
K Lehner, and
K Werdan, and
H Sedlmeier, and
P Zimmer, and
O Messerschmidt
July 1974,
Strahlentherapie,
K Lehner, and
K Werdan, and
H Sedlmeier, and
P Zimmer, and
O Messerschmidt
October 1974,
Strahlentherapie,
K Lehner, and
K Werdan, and
H Sedlmeier, and
P Zimmer, and
O Messerschmidt
December 1975,
British journal of cancer,
