BIOMAT Database Logo BIOMAT Database Logo

Morphologic variations in human leukemic lymphoblasts (CCRF-CEM cells) after long-term culture and exposure to chemotherapeutic agents. A study with the electron microscope. 1966

B G Uzman, and G E Foley, and S Farber, and H Lazarus

UI MeSH Term Description Entries
D007945 Leukemia, Lymphoid Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts. Leukemia, Lymphocytic,Lymphocytic Leukemia,Lymphoid Leukemia,Leukemias, Lymphocytic,Leukemias, Lymphoid,Lymphocytic Leukemias,Lymphoid Leukemias
D008214 Lymphocytes White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS. Lymphoid Cells,Cell, Lymphoid,Cells, Lymphoid,Lymphocyte,Lymphoid Cell
D008854 Microscopy, Electron Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen. Electron Microscopy
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000970 Antineoplastic Agents Substances that inhibit or prevent the proliferation of NEOPLASMS. Anticancer Agent,Antineoplastic,Antineoplastic Agent,Antineoplastic Drug,Antitumor Agent,Antitumor Drug,Cancer Chemotherapy Agent,Cancer Chemotherapy Drug,Anticancer Agents,Antineoplastic Drugs,Antineoplastics,Antitumor Agents,Antitumor Drugs,Cancer Chemotherapy Agents,Cancer Chemotherapy Drugs,Chemotherapeutic Anticancer Agents,Chemotherapeutic Anticancer Drug,Agent, Anticancer,Agent, Antineoplastic,Agent, Antitumor,Agent, Cancer Chemotherapy,Agents, Anticancer,Agents, Antineoplastic,Agents, Antitumor,Agents, Cancer Chemotherapy,Agents, Chemotherapeutic Anticancer,Chemotherapy Agent, Cancer,Chemotherapy Agents, Cancer,Chemotherapy Drug, Cancer,Chemotherapy Drugs, Cancer,Drug, Antineoplastic,Drug, Antitumor,Drug, Cancer Chemotherapy,Drug, Chemotherapeutic Anticancer,Drugs, Antineoplastic,Drugs, Antitumor,Drugs, Cancer Chemotherapy
D046508 Culture Techniques Methods of maintaining or growing biological materials in controlled laboratory conditions. These include the cultures of CELLS; TISSUES; organs; or embryo in vitro. Both animal and plant tissues may be cultured by a variety of methods. Cultures may derive from normal or abnormal tissues, and consist of a single cell type or mixed cell types. Culture Technique,Technique, Culture,Techniques, Culture

Related Publications

B G Uzman, and G E Foley, and S Farber, and H Lazarus
The response in vitro, of continuous cultures of human lymphoblasts (CCRF-CEM cells) to chemotherapeutic agents.
April 1967, Biochemical pharmacology,
B G Uzman, and G E Foley, and S Farber, and H Lazarus
Auromomycin-induced DNA damage and repair in human leukemic lymphoblasts (CCRF-CEM cells).
February 1986, Cancer research,
B G Uzman, and G E Foley, and S Farber, and H Lazarus
Studies on the nuclei of cultured human leukemic lymphoblasts (CCRF-CEM cells): method of isolation.
January 1968, Experimental cell research,
B G Uzman, and G E Foley, and S Farber, and H Lazarus
Sensitivity of cultured human lymphoblasts (CCRF-CEM cells) to inhibition by thymidine.
September 1966, Experimental cell research,
B G Uzman, and G E Foley, and S Farber, and H Lazarus
Electron microscope study of human leukemic cells in tissue culture.
January 1968, Bibliotheca haematologica,
B G Uzman, and G E Foley, and S Farber, and H Lazarus
Induction of apoptosis by iron deprivation in human leukemic CCRF-CEM cells.
May 1995, Experimental hematology,
B G Uzman, and G E Foley, and S Farber, and H Lazarus
In vitro inhibition of human leukemic cells (CCRF-CEM) by agarose-immobilized neocarzinostatin.
October 1977, Cancer research,
B G Uzman, and G E Foley, and S Farber, and H Lazarus
Human leukemic cells in tissue culture: an electron microscope survey.
December 1967, Cancer research,
B G Uzman, and G E Foley, and S Farber, and H Lazarus
Transport of folate compounds by leukemic cells. Evidence for a single influx carrier for methotrexate, 5-methyltetrahydrofolate, and folate in CCRF-CEM human lymphoblasts.
September 1987, Biochemical pharmacology,
B G Uzman, and G E Foley, and S Farber, and H Lazarus
Molecular and karyological analysis of methotrexate-resistant and -sensitive human leukemic CCRF-CEM cells.
January 1985, Cancer research,
Copied contents to your clipboard!