-transparent.png){kind=logo}
In chicks with cannulae chronically implanted into the III cerebral ventricle, the effects of a single dose (10 micrograms) of beta-endorphin on GABA and free glutamic acid content, GAD and GABA-T activities in the diencephalon, brain-stem and brain hemispheres were studied at the time of maximal behavioural stuporous state and analgesia. A significant decrease in GABA concentration both in the diencephalon and brain-stem, accompanied by a significant increase in GABA-T activity in the same areas, was shown to occur. No changes were observed in GAD activity and in glutamic acid content in the studied areas of the brain. In conclusion, present experiments suggest that some central effects of a beta-endorphin may be due to an interference with GABA-ergic transmission.
G Nisticò, and
R M Di Giorgio, and
D Rotiroti, and
F Naccari, and
A Calatroni
July 1979,
Journal of neurochemistry,
G Nisticò, and
R M Di Giorgio, and
D Rotiroti, and
F Naccari, and
A Calatroni
February 1981,
Research communications in chemical pathology and pharmacology,
G Nisticò, and
R M Di Giorgio, and
D Rotiroti, and
F Naccari, and
A Calatroni
June 1981,
Naunyn-Schmiedeberg's archives of pharmacology,
G Nisticò, and
R M Di Giorgio, and
D Rotiroti, and
F Naccari, and
A Calatroni
May 1989,
Experientia,
G Nisticò, and
R M Di Giorgio, and
D Rotiroti, and
F Naccari, and
A Calatroni
September 1978,
Life sciences,
G Nisticò, and
R M Di Giorgio, and
D Rotiroti, and
F Naccari, and
A Calatroni
August 1982,
Brain research,
G Nisticò, and
R M Di Giorgio, and
D Rotiroti, and
F Naccari, and
A Calatroni
January 1985,
Neuroscience letters,
G Nisticò, and
R M Di Giorgio, and
D Rotiroti, and
F Naccari, and
A Calatroni
October 1979,
Neuropharmacology,
G Nisticò, and
R M Di Giorgio, and
D Rotiroti, and
F Naccari, and
A Calatroni
January 1982,
Progress in brain research,
G Nisticò, and
R M Di Giorgio, and
D Rotiroti, and
F Naccari, and
A Calatroni
December 2006,
The Journal of steroid biochemistry and molecular biology,
