Comparative study of rigid vs flexible pneumatic artificial blood pumps. 1979

M Nosé, and A K Vakamudi, and T Kudo, and T Akutsu, and N H Hwang

For HR in the range of 70--110 beats/min, and same driving conditions, the pump with rigid housing produced a maximum of 15% greater CO than that with the soft housing, against an arterial pressure of 125/75 mm Hg. All 3 pumps exhibited greater sensitivity in function curves for HR in the range of 90--110 beats/min. The greatest sensitivity point in the function curve, for the rigid housing pump was found to be independent of HR change in the range of 90--110 beats/min. However, with an increase in HR the function curves shifted to the right in the case of soft housing pumps. In other words, greater atrial pressure was required to obtain the same CO with an increase in HR. The linear relationship found between CO and HR in flexible and soft housing pumps was very advantageous for controlling CO, whenever such change was required. In all 3 hearts there was a decrease in pulse pressure with an increase in HR. The decrease in pulse pressure was primarily due to the increase in diastolic pressure, while systolic pressure remained almost constant at all HRs. Since these experiments were conducted in a test circulatory system using an aqueous-glycerin solution, information on the degree of hemolysis was not addressed in this report.

UI MeSH Term Description Entries
D008768 Methylmethacrylates The methyl esters of methacrylic acid that polymerize easily and are used as tissue cements, dental materials, and absorbent for biological substances.
D008955 Models, Cardiovascular Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment. Cardiovascular Model,Cardiovascular Models,Model, Cardiovascular
D011140 Polyurethanes A group of thermoplastic or thermosetting polymers containing polyisocyanate. They are used as ELASTOMERS, as coatings, as fibers and as foams. Polyisocyanates,Ostamer,Pellethane,Spandex,Ostamers,Pellethanes,Polyisocyanate,Polyurethane,Spandices
D001775 Blood Circulation The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM. Blood Flow,Circulation, Blood,Blood Flows,Flow, Blood
D001794 Blood Pressure PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS. Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D002302 Cardiac Output The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat). Cardiac Outputs,Output, Cardiac,Outputs, Cardiac
D004548 Elasticity Resistance and recovery from distortion of shape.
D006339 Heart Rate The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D006354 Heart, Artificial A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (Dorland, 28th ed) Artificial Heart,Artificial Hearts,Hearts, Artificial
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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