Mode of delivery and the lecithin/sphingomyelin ratio. 1979

P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson

Babies born by elective Caesarean section are more likely to develop the respiratory distress syndrome that babies born vaginally. We studied the amniotic fluid and pharyngeal lecithin/sphingomyelin (L/S) ratios in three groups of babies born at term: 20 were delivered vaginally after elective induction of labour; 20 were delivered by elective Caesarean section; and 14 by Caesarean section after spontaneous onset of labour. Babies born after induction of labour had higher pharyngeal L/S ratios than babies born by elective Caesarean section. Those born by Caesarean section after spontaneous onset of labour had significantly higher pharyngeal L/S ratios than those in both of the elective delivery groups. There were no significant differences in the amniotic fluid L/S ratios of the two groups who underwent elective delivery. Regression analysis showed a significant relationship between length of labour and increase in the L/S ratio. These results indicate that, during labour, there is a release of fetal lung surfactant into the airways.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007751 Labor, Induced Artificially induced UTERINE CONTRACTION. Induced Labor,Induction of Labor,Labor Induced,Labor Induction,Induced, Labor,Induction, Labor,Inductions, Labor,Labor Inductions
D010614 Pharynx A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx). Throat,Pharynxs,Throats
D010713 Phosphatidylcholines Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety. Choline Phosphoglycerides,Choline Glycerophospholipids,Phosphatidyl Choline,Phosphatidyl Cholines,Phosphatidylcholine,Choline, Phosphatidyl,Cholines, Phosphatidyl,Glycerophospholipids, Choline,Phosphoglycerides, Choline
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D012127 Respiratory Distress Syndrome, Newborn A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause. Infantile Respiratory Distress Syndrome,Neonatal Respiratory Distress Syndrome,Respiratory Distress Syndrome, Infant
D002585 Cesarean Section Extraction of the FETUS by means of abdominal HYSTEROTOMY. Abdominal Delivery,Delivery, Abdominal,C-Section (OB),Caesarean Section,Postcesarean Section,Abdominal Deliveries,C Section (OB),C-Sections (OB),Caesarean Sections,Cesarean Sections,Deliveries, Abdominal
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000653 Amniotic Fluid A clear, yellowish liquid that envelopes the FETUS inside the sac of AMNION. In the first trimester, it is likely a transudate of maternal or fetal plasma. In the second trimester, amniotic fluid derives primarily from fetal lung and kidney. Cells or substances in this fluid can be removed for prenatal diagnostic tests (AMNIOCENTESIS). Amniotic Fluid Index,Amniotic Fluid Indices,Amniotic Fluids,Fluid Index, Amniotic,Fluid Indices, Amniotic,Fluid, Amniotic,Fluids, Amniotic,Index, Amniotic Fluid,Indices, Amniotic Fluid

Related Publications

P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson
December 1998, American journal of obstetrics and gynecology,
P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson
March 1973, American journal of obstetrics and gynecology,
P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson
November 1983, British journal of obstetrics and gynaecology,
P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson
November 1983, British journal of obstetrics and gynaecology,
P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson
June 1984, British journal of obstetrics and gynaecology,
P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson
January 1984, American journal of obstetrics and gynecology,
P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson
January 1982, Acta geneticae medicae et gemellologiae,
P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson
January 1979, Gynecologic and obstetric investigation,
P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson
January 1978, Acta obstetricia et gynecologica Scandinavica. Supplement,
P Callen, and S Goldsworthy, and L Graves, and D Harvey, and H Mellows, and C Parkinson
December 1975, Lancet (London, England),
Copied contents to your clipboard!