Biomaterial Database

A ge distribution of antibodies to animal influenza A viruses in human sera. 1968

A S Gorbunova, and T V Pysina

A total of 394 sera from persons in different age-groups among the inhabitants of the Vladivostok area were studied by the haemagglutination-inhibition (HI) test for the presence of influenza antibodies. Each serum was examined against 12 antigens of influenza A virus of human (A0, A1, and 2 strains of A2) and animal (1 swine, 2 equine and 5 avian strains) origin. All the sera were collected 8-9 months after the outbreak of A2 influenza in 1965. Antibodies to some animal viruses were present: Swine/Iowa, Equi/2/Miami, Tern/South Africa and Chicken/Scotland strains; negative results were found to Equi/1/Prague, Duck/England and Duck/Czechoslovakia and fowl plague strains. The pattern of HI antibody distribution to animal strains showed an increase in the range in relation to age; the largest was found in the older age-group (70 years and over).The authors suggest that antibodies in the human sera to animal strains are not necessarily an indication of past infection with those strains.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009975	Orthomyxoviridae	A family of RNA viruses causing INFLUENZA and other respiratory diseases. Orthomyxoviridae includes INFLUENZAVIRUS A; INFLUENZAVIRUS B; INFLUENZAVIRUS C; INFLUENZAVIRUS D; ISAVIRUS; and THOGOTOVIRUS.	Influenza Viruses,Myxoviruses,Orthomyxoviruses,Influenza Virus,Myxovirus,Orthomyxovirus
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D006385	Hemagglutination Inhibition Tests	Serologic tests in which a known quantity of antigen is added to the serum prior to the addition of a red cell suspension. Reaction result is expressed as the smallest amount of antigen which causes complete inhibition of hemagglutination.	Hemagglutination Inhibition Test,Inhibition Test, Hemagglutination,Inhibition Tests, Hemagglutination,Test, Hemagglutination Inhibition,Tests, Hemagglutination Inhibition
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000367	Age Factors	Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.	Age Reporting,Age Factor,Factor, Age,Factors, Age