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A young woman with acute intermittent porphyria in profound relapse and severe nervous and respiratory involvement was treated by intravenous infusions of hematin, followed by improvement of symptoms. The diet with high carbohydrate and protein content and a B-adrenergic blocking agent, not showed any beneficial effect on acute attack. The infusion of hematin was followed by a lowering effect on urine porphybilinogen and delta-aminolevulinic acid and clinical improvement. The return to normal of porphyrin precursors in the urine was accompanied by almost complete clinical remission. The relationship of remission and repression of delta-aminolevulinic acid, decrease of urinary levels of porphyrin precursors, pulmonaries tests and electromyograms, were discussed.
P E Marchiori, and
J L de Assis, and
M Scaff, and
L G Do Serro-Azul, and
E C Moraes, and
L A Bacheschi, and
N Yassuda
January 1981,
Zentralblatt fur Gynakologie,
P E Marchiori, and
J L de Assis, and
M Scaff, and
L G Do Serro-Azul, and
E C Moraes, and
L A Bacheschi, and
N Yassuda
June 1979,
Medicina clinica,
P E Marchiori, and
J L de Assis, and
M Scaff, and
L G Do Serro-Azul, and
E C Moraes, and
L A Bacheschi, and
N Yassuda
December 1981,
Annals of internal medicine,
P E Marchiori, and
J L de Assis, and
M Scaff, and
L G Do Serro-Azul, and
E C Moraes, and
L A Bacheschi, and
N Yassuda
August 1979,
Bratislavske lekarske listy,
P E Marchiori, and
J L de Assis, and
M Scaff, and
L G Do Serro-Azul, and
E C Moraes, and
L A Bacheschi, and
N Yassuda
January 1980,
Medicina clinica,
P E Marchiori, and
J L de Assis, and
M Scaff, and
L G Do Serro-Azul, and
E C Moraes, and
L A Bacheschi, and
N Yassuda
August 1987,
Deutsche medizinische Wochenschrift (1946),
P E Marchiori, and
J L de Assis, and
M Scaff, and
L G Do Serro-Azul, and
E C Moraes, and
L A Bacheschi, and
N Yassuda
December 1981,
Medicina clinica,
P E Marchiori, and
J L de Assis, and
M Scaff, and
L G Do Serro-Azul, and
E C Moraes, and
L A Bacheschi, and
N Yassuda
January 1977,
Medicinski pregled,
P E Marchiori, and
J L de Assis, and
M Scaff, and
L G Do Serro-Azul, and
E C Moraes, and
L A Bacheschi, and
N Yassuda
March 1978,
Singapore medical journal,
P E Marchiori, and
J L de Assis, and
M Scaff, and
L G Do Serro-Azul, and
E C Moraes, and
L A Bacheschi, and
N Yassuda
March 2020,
Biomedica : revista del Instituto Nacional de Salud,
