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The effect of combined topical applications of a steroid and nonsteroid anti-inflammatory agent on erythema induced by ultraviolet-B irradiation (UV-B) was evaluated. In human volunteers, the combination more effectively suppressed UV-B--induced erythema than either agent alone. When applied singly, the nonsteroid agent was far more effective than the steroid. The combination, or either agent alone, was most effective when applied immediately after irradiation. This study demonstrates that for the treatment of UV-B--induced erythema, the anti-inflammation effects of these two classes of anti-inflammatory agents are greater when used in combination than when either agent is used alone. However, the effect of the combination in this study is not sufficiently long-lasting to be therapeutically useful.
W H Eaglestein, and
L D Ginsberg, and
P M Mertz
January 1966,
Annual review of pharmacology,
W H Eaglestein, and
L D Ginsberg, and
P M Mertz
January 1968,
Annual review of pharmacology,
W H Eaglestein, and
L D Ginsberg, and
P M Mertz
January 1970,
Annual review of pharmacology,
W H Eaglestein, and
L D Ginsberg, and
P M Mertz
January 1973,
Annual review of pharmacology,
W H Eaglestein, and
L D Ginsberg, and
P M Mertz
October 1988,
Sheng li ke xue jin zhan [Progress in physiology],
W H Eaglestein, and
L D Ginsberg, and
P M Mertz
January 1978,
La Revue du praticien,
W H Eaglestein, and
L D Ginsberg, and
P M Mertz
January 1981,
Terapevticheskii arkhiv,
W H Eaglestein, and
L D Ginsberg, and
P M Mertz
August 1981,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
W H Eaglestein, and
L D Ginsberg, and
P M Mertz
October 1969,
Revista espanola de reumatismo y enfermedades osteoarticulares,
W H Eaglestein, and
L D Ginsberg, and
P M Mertz
May 1967,
Gaceta medica de Mexico,
