Uricosuric drugs, with special reference to probenecid and sulfinpyrazone. 1966

A B Gutman

UI MeSH Term Description Entries
D008297 Male Males
D011339 Probenecid The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy. Benecid,Benemid,Benuryl,Pro-Cid,Probecid,Probenecid Weimer
D006073 Gout Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi. Gouts
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013442 Sulfinpyrazone A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties. Sulfoxyphenylpyrazolidin,Anturan,Anturane,Apo-Sulfinpyrazone,Nu-Sulfinpyrazone,Sulphinpyrazone,Apo Sulfinpyrazone,Nu Sulfinpyrazone
D014528 Uricosuric Agents Gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma. Uricosuric Agent,Agent, Uricosuric,Agents, Uricosuric

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