Biomaterial Database

Efficacy of anthelmintics against cattle nematodes. 1979

A P Callinan, and L J Cummins

The efficacies of fenbendazole and thiabendazole against artifically acquired cattle nematodes and the efficacies of fenbendazole, prabendazole and levamisole against naturally acquired cattle nematodes were studied in western Victoria. Fenbendazole significantly (P less than 0.05) reduced numbers of late and early fourth stage larvae (greater than 96%), artificially acquired Cooperla spp (100%) and naturally acquired adult Ostertagia ostertagi (98%) and Trichostrongylus axei (90%). Thiabendazole significantly reduced numbers of artificially acquired late fourth stage larvae (83%) and parbendazole significantly reduced numbers of adult O. ostertagi (72%) in one group of cattle. Fenbendazole was the most effective anthelmintic.

UI	MeSH Term	Description	Entries
D010029	Ostertagiasis	A disease of herbivorous mammals, particularly cattle and sheep, caused by stomach worms of the genus OSTERTAGIA.	Ostertagiases
D002417	Cattle	Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.	Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D002418	Cattle Diseases	Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus.	Bovine Diseases,Bovine Disease,Cattle Disease,Disease, Bovine,Disease, Cattle,Diseases, Bovine,Diseases, Cattle
D005260	Female		Females
D005273	Fenbendazole	Antinematodal benzimidazole used in veterinary medicine.	Panacur,Phenbendasol
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001562	Benzimidazoles	Compounds with a BENZENE fused to IMIDAZOLES.
D013827	Thiabendazole	2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for STRONGYLOIDIASIS. It has CENTRAL NERVOUS SYSTEM side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)	Tiabendazol,2-(4'-Thiazolyl)Benzimidazole,Mintesol,Mintezol,Omnizole,Thibendole
D014252	Trichostrongyloidiasis	Infection by roundworms of the superfamily TRICHOSTRONGYLOIDEA, including the genera TRICHOSTRONGYLUS; OSTERTAGIA; Cooperia, HAEMONCHUS; Nematodirus, Hyostrongylus, and DICTYOCAULUS.	Trichostrongyloidiases