Methods of studying lobar and segmental function of the lung in man. 1979

S J Williams, and R J Pierce, and N J Davies, and D M Denison

Making the decision whether a patient with chest disease can undergo lung surgery may be easier if the anatomical extent of the disease and the functional effects of resection can be estimated. Although information can be gained by non-invasive physiological studies of lung function of a routine kind, these cannot define the anatomical extent of the disease or distinguish the relative influence of affected and unaffected parts as estimates of lung function. Whole lung ventilation and perfusion scans provide immediate topographic information but have limited resolution and anatomical accuracy, particularly when the architecture of the lung is disturbed by disease. Bronchoscopy gives direct visual information about the more central airways but little or none about the function of the areas they serve. This paper gives brief descriptions of a series of procedures which could help in assessing the feasibility of lung surgery. The size, shape and volumes of individual lungs and lobes can be estimated from plain chest radiographs. Corresponding information about individual segments, and about lobes not delineated by normal X-ray, can be obtained using radio-active krypton 81m and a gamma camera during otherwise routine fibreoptic bronchscopy segments can be determined by simple single-breath manoeuvres at bronchoscopy using a respiratory mass spectrometer. The radio-isotope and spectrometric tests can be obtained in the same breath. The spectrometric tests can be recorded from more than one part of the lung within the same breath. All of the procedures give information in terms of anatomical units of interest to the surgeon.

UI MeSH Term Description Entries
D007726 Krypton A noble gas that is found in the atmosphere. It has the atomic symbol Kr, atomic number 36, atomic weight 83.80, and has been used in electric bulbs.
D008168 Lung Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood. Lungs
D008171 Lung Diseases Pathological processes involving any part of the LUNG. Pulmonary Diseases,Disease, Pulmonary,Diseases, Pulmonary,Pulmonary Disease,Disease, Lung,Diseases, Lung,Lung Disease
D008176 Lung Volume Measurements Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle. Lung Capacities,Lung Volumes,Capacity, Lung,Lung Capacity,Lung Volume,Lung Volume Measurement,Measurement, Lung Volume,Volume, Lung
D008297 Male Males
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011650 Pulmonary Alveoli Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place. Alveoli, Pulmonary,Alveolus, Pulmonary,Pulmonary Alveolus
D011652 Pulmonary Circulation The circulation of the BLOOD through the LUNGS. Pulmonary Blood Flow,Respiratory Circulation,Circulation, Pulmonary,Circulation, Respiratory,Blood Flow, Pulmonary,Flow, Pulmonary Blood,Pulmonary Blood Flows
D011868 Radioisotopes Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Daughter Isotope,Daughter Nuclide,Radioactive Isotope,Radioactive Isotopes,Radiogenic Isotope,Radioisotope,Radionuclide,Radionuclides,Daughter Nuclides,Daugter Isotopes,Radiogenic Isotopes,Isotope, Daughter,Isotope, Radioactive,Isotope, Radiogenic,Isotopes, Daugter,Isotopes, Radioactive,Isotopes, Radiogenic,Nuclide, Daughter,Nuclides, Daughter

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