Correction of the maternal effect linked to the ac mutation, by injury of the egg, in the salamander Pleurodeles waltlii. 1979

M Fernandez

At the gastrula stage, deep irregular furrows appear on the animal hemisphere in embryos arising from ac/ac females and characterize a maternal effect (Beetschen, 1970). Disturbed morphogenetic movements (epiboly and invagination) frequently elicit exogastrulation or anomalies of later embryonic development. Pricking the animal hemisphere of the uncleaved egg with a micropipette prevents the occurrence of anomalies during gastrulation and neurulation in many embryos. Injection of normal oocyte nuclear sap or of normal egg cytoplasm into mutant female eggs does not improve that result. The partial correction of the maternal effect therefore appears to be consecutive to the injury of the cortical cytoplasm and/or the plasma membrane. Assuming that activation could be deficient, an electric shock was applied to freshly laid fertilized mutant eggs. It did not correct ectodermal anomalies but nevertheless seemed to increase the corrective effect of pricking when both treatments were applied.

UI MeSH Term Description Entries
D008297 Male Males
D009024 Morphogenesis The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.
D009154 Mutation Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations. Mutations
D002467 Cell Nucleus Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed) Cell Nuclei,Nuclei, Cell,Nucleus, Cell
D003593 Cytoplasm The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990) Protoplasm,Cytoplasms,Protoplasms
D004475 Ectoderm The outer of the three germ layers of an embryo. Apical Ectodermal Ridge,Apical Ectodermal Ridges,Ectodermal Ridge, Apical,Ectoderms
D005260 Female Females
D005775 Gastrula The developmental stage that follows BLASTULA or BLASTOCYST. It is characterized by the morphogenetic cell movements including invagination, ingression, and involution. Gastrulation begins with the formation of the PRIMITIVE STREAK, and ends with the formation of three GERM LAYERS, the body plan of the mature organism. Archenteron,Blastopore,Gastrocoele,Primitive Gut,Archenterons,Blastopores,Gastrocoeles,Gastrulas,Gut, Primitive,Guts, Primitive,Primitive Guts
D005796 Genes A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms. Cistron,Gene,Genetic Materials,Cistrons,Genetic Material,Material, Genetic,Materials, Genetic
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

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