Serum folate and folic acid binding proteins in iron deficiency anaemia. 1979

S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat

Serum and red cell folate and folic acid binding protein (FABP) concentrations were determined on 20 iron deficiency anaemic children of both sexes aged 6--12 years. All cases had haemoglobin level less than 12 gm% or haematocrit less than 36% with low serum iron and elevated unsaturated iron binding capacity. Serum folate levels in the anaemic group was not significantly different from that of normal subjects while red cell folate level was significantly lower in the anaemic group. However, all cases had red cell folate levels higher than 100 ng/ml. There was a direct relationship between the haemoglobin concentration and serum folate level. Serum FABP level in the anaemic group was found to be significantly higher than that of normal subjects and showed no correlation with haemoglobin, haematocrit, serum or red cell folate levels. The significance of elevated serum FABP was discussed.

UI MeSH Term Description Entries
D008297 Male Males
D002352 Carrier Proteins Proteins that bind or transport specific substances in the blood, within the cell, or across cell membranes. Binding Proteins,Carrier Protein,Transport Protein,Transport Proteins,Binding Protein,Protein, Carrier,Proteins, Carrier
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005260 Female Females
D005492 Folic Acid A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. Pteroylglutamic Acid,Vitamin M,Folacin,Folate,Folic Acid, (D)-Isomer,Folic Acid, (DL)-Isomer,Folic Acid, Calcium Salt (1:1),Folic Acid, Monopotassium Salt,Folic Acid, Monosodium Salt,Folic Acid, Potassium Salt,Folic Acid, Sodium Salt,Folvite,Vitamin B9,B9, Vitamin
D006400 Hematocrit The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value. Erythrocyte Volume, Packed,Packed Red-Cell Volume,Erythrocyte Volumes, Packed,Hematocrits,Packed Erythrocyte Volume,Packed Erythrocyte Volumes,Packed Red Cell Volume,Packed Red-Cell Volumes,Red-Cell Volume, Packed,Red-Cell Volumes, Packed,Volume, Packed Erythrocyte,Volume, Packed Red-Cell,Volumes, Packed Erythrocyte,Volumes, Packed Red-Cell
D006454 Hemoglobins The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements. Eryhem,Ferrous Hemoglobin,Hemoglobin,Hemoglobin, Ferrous
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000747 Anemia, Hypochromic Anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular hemoglobin concentration is less than normal. The individual cells contain less hemoglobin than they could have under optimal conditions. Hypochromic anemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. It can also be caused by infections or other diseases, therapeutic drugs, lead poisoning, and other conditions. (Stedman, 25th ed; from Miale, Laboratory Medicine: Hematology, 6th ed, p393) Chlorosis,Anemias, Hypochromic,Chloroses,Hypochromic Anemia,Hypochromic Anemias

Related Publications

S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat
February 1971, British journal of haematology,
S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat
November 1971, The Indian journal of medical research,
S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat
April 1974, The American journal of clinical nutrition,
S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat
January 1973, Scandinavian journal of haematology,
S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat
January 1974, Acta haematologica,
S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat
July 1959, British journal of haematology,
S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat
November 1963, Postgraduate medical journal,
S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat
September 1980, The Southeast Asian journal of tropical medicine and public health,
S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat
August 1973, Blood,
S Areekul, and K Ratanabanangkoon, and P Hathirat, and C Cheeramakara, and K Srisukawat
April 1976, The Journal of the Association of Physicians of India,
Copied contents to your clipboard!