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Total synthesis of heterocyclic steroids, Part II. Synthesis of (+/-)-17-thia-3-methoxy-8 alpha, 14 beta-estra-1,3,5(10)-triene-17-dioxide. 1979

P S Jogdeo, and G V Bhide

2-Methyl-3-oxothiophane-1-dioxide (II) was prepared and was used as the D ring precursor in the total synthesis of the title compound via modified Torgov synthesis.

UI MeSH Term Description Entries
D004963 Estrenes Unsaturated derivatives of the ESTRANES with methyl groups at carbon-13, with no carbon at carbon-10, and with no more than one carbon at carbon-17. They must contain one or more double bonds. 19-Norandrostenes,19 Norandrostenes
D013260 Steroids, Heterocyclic Steroidal compounds in which one or more carbon atoms in the steroid ring system have been substituted with non-carbon atoms. Heterocyclic Steroids
D013876 Thiophenes A monocyclic heteroarene furan in which the oxygen atom is replaced by a sulfur. Thiophene

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