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The diagnostic efficacy of bone-marrow culture, serial blood cultures and agglutination tests was compared in a prospective study of 60 patients with typhoid fever, two thirds of whom had received prior antibacterial therapy. Salmonella typhi was recovered from marrow cultures in 95% of patients but blood cultures were positive in only 43.3% (P less than 0.001). Agglutination tests were eventually diagnostic in 56.7% of patients, but in only 25% at the time of admission. If procedures had been limited to blood cultures and agglutination tests, diagnosis would have been missed in 21.7% of cases. The efficacy of marrow cultures was affected not by the duration of disease but by the extent of antibacterial therapy before presentation. Bacteriological recovery was faster from marrow cultures.
J G Guerra-Caceres, and
E Gotuzzo-Herencia, and
E Crosby-Dagnino, and
M Miro-Quesada, and
C Carrillo-Parodi
March 1953,
Klinicheskaia meditsina,
J G Guerra-Caceres, and
E Gotuzzo-Herencia, and
E Crosby-Dagnino, and
M Miro-Quesada, and
C Carrillo-Parodi
February 1994,
Journal of Korean medical science,
J G Guerra-Caceres, and
E Gotuzzo-Herencia, and
E Crosby-Dagnino, and
M Miro-Quesada, and
C Carrillo-Parodi
June 1982,
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J G Guerra-Caceres, and
E Gotuzzo-Herencia, and
E Crosby-Dagnino, and
M Miro-Quesada, and
C Carrillo-Parodi
December 1951,
Sovetskaia meditsina,
J G Guerra-Caceres, and
E Gotuzzo-Herencia, and
E Crosby-Dagnino, and
M Miro-Quesada, and
C Carrillo-Parodi
September 1982,
Boletin medico del Hospital Infantil de Mexico,
J G Guerra-Caceres, and
E Gotuzzo-Herencia, and
E Crosby-Dagnino, and
M Miro-Quesada, and
C Carrillo-Parodi
August 1977,
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J G Guerra-Caceres, and
E Gotuzzo-Herencia, and
E Crosby-Dagnino, and
M Miro-Quesada, and
C Carrillo-Parodi
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J G Guerra-Caceres, and
E Gotuzzo-Herencia, and
E Crosby-Dagnino, and
M Miro-Quesada, and
C Carrillo-Parodi
January 1954,
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J G Guerra-Caceres, and
E Gotuzzo-Herencia, and
E Crosby-Dagnino, and
M Miro-Quesada, and
C Carrillo-Parodi
September 1959,
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J G Guerra-Caceres, and
E Gotuzzo-Herencia, and
E Crosby-Dagnino, and
M Miro-Quesada, and
C Carrillo-Parodi
August 1971,
North Carolina medical journal,
