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The haemodynamic affects of dobutamine (DB) (5 microgram/kg/min), isoproterenol (I) (0.02 microgram/kg/min), dopamine (DP) (5 microgram/kg/min), were studied in 12 patients with coronary artery disease randomly divided in two groups of 6 patients. In one group each patient received DB and I, in the other group each patient received DB and DP. The following parameters were measured: heart rate, aortic blood pressure, left ventricular pressure, left ventricular dp/dt, pulmonary arterial and wedge pressure, cardiac output, stroke volume, peripheral and pulmonary vascular resistances. In both groups either I and DP increased significantly heart rate whereas DB did not modifie it. DB caused a larger increase of dp/dt max and of stroke volume as compared to I and DP. These data confirm that DB possesses an inotropic effect greater than I and DP without any significant positive chronotropic effect in patients with coronary artery disease.
E Ambrosioni, and
A Maresta, and
B Magnani
March 1980,
Nihon yakurigaku zasshi. Folia pharmacologica Japonica,
E Ambrosioni, and
A Maresta, and
B Magnani
July 1979,
Der Anaesthesist,
E Ambrosioni, and
A Maresta, and
B Magnani
March 1979,
Nihon yakurigaku zasshi. Folia pharmacologica Japonica,
E Ambrosioni, and
A Maresta, and
B Magnani
January 1978,
Annales de l'anesthesiologie francaise,
E Ambrosioni, and
A Maresta, and
B Magnani
September 1979,
Pediatric research,
E Ambrosioni, and
A Maresta, and
B Magnani
November 1979,
[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai,
E Ambrosioni, and
A Maresta, and
B Magnani
October 1977,
Zeitschrift fur Kardiologie,
E Ambrosioni, and
A Maresta, and
B Magnani
July 1979,
Masui. The Japanese journal of anesthesiology,
E Ambrosioni, and
A Maresta, and
B Magnani
February 1982,
European heart journal,
E Ambrosioni, and
A Maresta, and
B Magnani
June 1984,
Research communications in chemical pathology and pharmacology,
