Biomaterial Database

Precipitating and non-precipitating complement consuming IgG subclass antibodies in pigeon breeders' disease. 1979

G de Ridder, and L Berrens

The sera of patients with pigeon breeder's disease usually contain precipitating serum factors as well as human complement consuming factors as shown by incubation of the serum with pigeon dropping antigens. Although a single serum factor, possibly an IgG antibody, might account for both phenomena, affinity chromatography experiments revealed that the sera of patients with pigeon breeders' disease contain non-recipitating, human complement consuming, serum factors besides precipitating serum factors which are also capable of complement consumption. The non-precipitating serum factors most likely belong to the IgG3 immunoglobulin subclass, whereas the precipitating antibodies belong to the subclasses IgG1 and IgG2.

UI	MeSH Term	Description	Entries
D007074	Immunoglobulin G	The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.	Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D002850	Chromatography, Gel	Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.	Chromatography, Exclusion,Chromatography, Gel Permeation,Chromatography, Molecular Sieve,Gel Filtration,Gel Filtration Chromatography,Chromatography, Size Exclusion,Exclusion Chromatography,Gel Chromatography,Gel Permeation Chromatography,Molecular Sieve Chromatography,Chromatography, Gel Filtration,Exclusion Chromatography, Size,Filtration Chromatography, Gel,Filtration, Gel,Sieve Chromatography, Molecular,Size Exclusion Chromatography
D003165	Complement System Proteins	Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that creates the COMPLEMENT MEMBRANE ATTACK COMPLEX. Included are glycoproteins in the various pathways of complement activation (CLASSICAL COMPLEMENT PATHWAY; ALTERNATIVE COMPLEMENT PATHWAY; and LECTIN COMPLEMENT PATHWAY).	Complement Proteins,Complement,Complement Protein,Hemolytic Complement,Complement, Hemolytic,Protein, Complement,Proteins, Complement,Proteins, Complement System
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000542	Alveolitis, Extrinsic Allergic	A common interstitial lung disease caused by hypersensitivity reactions of PULMONARY ALVEOLI after inhalation of and sensitization to environmental antigens of microbial, animal, or chemical sources. The disease is characterized by lymphocytic alveolitis and granulomatous pneumonitis.	Allergic Alveolitis, Extrinsic,Hypersensitivity Pneumonitis,Pneumonitis, Hypersensitivity,Allergic Alveolitides, Extrinsic,Alveolitides, Extrinsic Allergic,Extrinsic Allergic Alveolitides,Extrinsic Allergic Alveolitis,Hypersensitivity Pneumonitides,Pneumonitides, Hypersensitivity
D000906	Antibodies	Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).
D001716	Bird Fancier's Lung	A form of alveolitis or pneumonitis due to an acquired hypersensitivity to inhaled avian antigens, usually proteins in the dust of bird feathers and droppings.	Avian Hypersensitivity Pneumonitis,Budgerigar Fancier's Lung,Feather Duvet Lung,Hypersensitivity Pneumonitis, Avian,Pigeon Breeder's Lung,Pneumonitis, Hypersensitivity, Avian,Pneumonitis, Avian Hypersensitivity,Avian Hypersensitivity Pneumonitides,Bird Fancier Lung,Bird Fancier's Lungs,Bird Fanciers Lung,Budgerigar Fancier Lung,Budgerigar Fancier's Lungs,Budgerigar Fanciers Lung,Duvet Lung, Feather,Duvet Lungs, Feather,Feather Duvet Lungs,Hypersensitivity Pneumonitides, Avian,Lung, Bird Fancier's,Lung, Budgerigar Fancier's,Lung, Feather Duvet,Lung, Pigeon Breeder's,Lungs, Bird Fancier's,Lungs, Budgerigar Fancier's,Lungs, Feather Duvet,Lungs, Pigeon Breeder's,Pigeon Breeder Lung,Pigeon Breeder's Lungs,Pigeon Breeders Lung,Pneumonitides, Avian Hypersensitivity