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[Studies on anti-inflammatory agents. X. Stabilization of rat liver lysosome by 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c]pyridine (Y-3642)]. 1970

M Nakanishi, and H Imamura, and K Goto

UI MeSH Term Description Entries
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008247 Lysosomes A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured or undergoes MEMBRANE FUSION. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed). Autolysosome,Autolysosomes,Lysosome
D008297 Male Males
D008528 Mefenamic Acid A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase. Apo-Mefenamic,Contraflam,Coslan,Dysman,Mefac,Mefacit,Mefenaminic Acid,Mefic,Nu-Mefenamic,PMS-Mefenamic Acid,Parkemed,Pinalgesic,Ponalar,Ponalgic,Ponmel,Ponstan,Ponstan Forte,Ponstel,Ponsyl,Pontal,Acid, Mefenamic,Apo Mefenamic,Nu Mefenamic,PMS Mefenamic Acid
D010113 Oxyphenbutazone A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27) Hydroxyphenylbutazone,Diflamil,Oxyphenylbutazone,Tanderil
D010653 Phenylbutazone A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS. Diphenylbutazone,Fenilbutazon,Butacote,Butadion,Butadione,Butapirazol,Butapyrazole,Butazolidin
D011725 Pyridines Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
D005439 Flufenamic Acid An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16) Dignodolin,Acid, Flufenamic
D005966 Glucuronidase Endo-beta-D-Glucuronidase,Endoglucuronidase,Exo-beta-D-Glucuronidase,beta-Glucuronidase,Endo beta D Glucuronidase,Exo beta D Glucuronidase,beta Glucuronidase
D000135 Acid Phosphatase An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2. Acid beta-Glycerophosphatase,Acid beta Glycerophosphatase

Related Publications

M Nakanishi, and H Imamura, and K Goto
[Studies on anti-inflammatory agents. XIX. Metabolism of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno-(2,3-c) pyridine (Y-3642)].
September 1972, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Goto
[Studies on anti-inflammatory agents. XXI. The new metabolite of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine (Y-3642)].
April 1973, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Goto
[Studies on anti-inflammatory agents. 13. Distribution of 35S-2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c] pyridine (35S-Y-3642)].
September 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Goto
[Studies on anti-inflammatory agents. XVI. The N-debenzylation of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno (2,3-c) pyridine (Y-3642)].
May 1971, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Goto
[Studies on anti-inflammatory agents. XII. Metabolites of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c] pyridine (Y-3642) in human urine].
September 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Goto
[Studies on anti-inflammatory agents. V. Distribution of 2-amino-3-ethoxycarbonyl-6-benzyl(alpha-14C)-4,5,6,7-tetrahydrothieno-(2,3-c)pyridine (14C-Y-3642) in mice].
March 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Goto
[Studies on anti-inflammatory agents. VI. Absorption, Excretion and metabolism of 2-amino-3-ethoxycarbonyl-6-benzyl(alpha-14C)-4,5,6,7-tetrahydrothieno(2,3-c)pyridine (14C-Y-3642) in mice].
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M Nakanishi, and H Imamura, and K Goto
[Studies on anti-inflammatory agents. XV. Toxicological studies of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine hydrochloride. II].
November 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Goto
[Studies on anti-inflammatory agents. XIV. Toxicological studies of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine hydrochloride. I].
November 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Goto
[Studies on anti-inflammatory agents. XX. Metabolism of 35 S-2-amino-3-ethoxycarbonyl-4,5,6,7-tetrahydrothieno (2,3-c)-pyridine ( 35 S-nor-Y-3642) and 14 C-benzoic acid].
September 1972, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
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