Acetaminophen prodrugs. 3. Hydrolysis of carbonate and carboxylic acid esters in aqueous buffers.
1970
E S Rattie, and
E G Shami, and
L W Dittert, and
J V Swintosky
UI
MeSH Term
Description
Entries
D002021
Buffers
A chemical system that functions to control the levels of specific ions in solution. When the level of hydrogen ion in solution is controlled the system is called a pH buffer.
Buffer
D002254
Carbonates
Salts or ions of the theoretical carbonic acid, containing the radical CO2(3-). Carbonates are readily decomposed by acids. The carbonates of the alkali metals are water-soluble; all others are insoluble. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Carbonate
D000082
Acetaminophen
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.