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The possibility of transport of free and heparin-bound histamine along the concentration gradient through bimolecular lipid membranes (BLM) and the influence of various factors on it was studied. It was shown that histamine is capable of diffusing through BLM in the form of a singly charged cation. In contrast to histamine, neither heparin nor the histamine-heparin complex (HsHC) penetrates through BLM. It was established that the action of histamine-liberating factors -- increasing the ionic strength to 0.15 and the addition of trypsin to the solution -- on HsHC leads to the appearance of transport of histamine through the BLM as a result of an increase in the concentration of free histamine in solution.
K L Erzinkyan, and
M M Katz, and
S V Nizhnii
January 1979,
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia,
K L Erzinkyan, and
M M Katz, and
S V Nizhnii
November 1971,
Biophysical journal,
K L Erzinkyan, and
M M Katz, and
S V Nizhnii
January 1971,
Ukrains'kyi biokhimichnyi zhurnal,
K L Erzinkyan, and
M M Katz, and
S V Nizhnii
January 1963,
Annual review of physiology,
K L Erzinkyan, and
M M Katz, and
S V Nizhnii
January 1967,
Annual review of physiology,
K L Erzinkyan, and
M M Katz, and
S V Nizhnii
January 1959,
Annual review of physiology,
K L Erzinkyan, and
M M Katz, and
S V Nizhnii
January 1953,
Annual review of physiology,
K L Erzinkyan, and
M M Katz, and
S V Nizhnii
January 1965,
Annual review of physiology,
K L Erzinkyan, and
M M Katz, and
S V Nizhnii
January 1961,
Annual review of physiology,
K L Erzinkyan, and
M M Katz, and
S V Nizhnii
January 1955,
Annual review of physiology,
