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Pharmacological investigations of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine. 1970

M Nakanishi, and H Imamura, and K Ikegami, and K Goto

UI MeSH Term Description Entries
D007213 Indomethacin A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES. Amuno,Indocid,Indocin,Indomet 140,Indometacin,Indomethacin Hydrochloride,Metindol,Osmosin
D007249 Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. Innate Inflammatory Response,Inflammations,Inflammatory Response, Innate,Innate Inflammatory Responses
D008297 Male Males
D008528 Mefenamic Acid A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase. Apo-Mefenamic,Contraflam,Coslan,Dysman,Mefac,Mefacit,Mefenaminic Acid,Mefic,Nu-Mefenamic,PMS-Mefenamic Acid,Parkemed,Pinalgesic,Ponalar,Ponalgic,Ponmel,Ponstan,Ponstan Forte,Ponstel,Ponsyl,Pontal,Acid, Mefenamic,Apo Mefenamic,Nu Mefenamic,PMS Mefenamic Acid
D010653 Phenylbutazone A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS. Diphenylbutazone,Fenilbutazon,Butacote,Butadion,Butadione,Butapirazol,Butapyrazole,Butazolidin
D011485 Protein Binding The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments. Plasma Protein Binding Capacity,Binding, Protein
D011489 Protein Denaturation Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein. Denaturation, Protein,Denaturations, Protein,Protein Denaturations
D011725 Pyridines Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D001792 Blood Platelets Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation. Platelets,Thrombocytes,Blood Platelet,Platelet,Platelet, Blood,Platelets, Blood,Thrombocyte

Related Publications

M Nakanishi, and H Imamura, and K Ikegami, and K Goto
[Studies on anti-inflammatory agents. XIX. Metabolism of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno-(2,3-c) pyridine (Y-3642)].
September 1972, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Ikegami, and K Goto
[Studies on anti-inflammatory agents. XV. Toxicological studies of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine hydrochloride. II].
November 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Ikegami, and K Goto
[Studies on anti-inflammatory agents. XIV. Toxicological studies of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine hydrochloride. I].
November 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Ikegami, and K Goto
[Studies on anti-inflammatory agents. XXI. The new metabolite of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine (Y-3642)].
April 1973, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Ikegami, and K Goto
[Studies on anti-inflammatory agents. 13. Distribution of 35S-2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c] pyridine (35S-Y-3642)].
September 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Ikegami, and K Goto
[Studies on anti-inflammatory agents. XVI. The N-debenzylation of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno (2,3-c) pyridine (Y-3642)].
May 1971, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Ikegami, and K Goto
[Studies on anti-inflammatory agents. XII. Metabolites of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c] pyridine (Y-3642) in human urine].
September 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Ikegami, and K Goto
[Studies on anti-inflammatory agents. V. Distribution of 2-amino-3-ethoxycarbonyl-6-benzyl(alpha-14C)-4,5,6,7-tetrahydrothieno-(2,3-c)pyridine (14C-Y-3642) in mice].
March 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Nakanishi, and H Imamura, and K Ikegami, and K Goto
Effect of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno (2,3-C) pyridine (tinoridine) on fatty acid composition of liver lysosomes from a vitamin E deficient diet to rats.
December 1973, Japanese journal of pharmacology,
M Nakanishi, and H Imamura, and K Ikegami, and K Goto
[Studies on anti-inflammatory agents. VII. Absorption, distribution, excretion and metabolism of 2-amino-3-ethoxycarbonyl-6-benzyl(alpha-14C)-4,5,6,7-tetrahydrothieno(2,3-c)pyridine (14C-Y3642) in rats].
March 1970, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
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